Kratom

Major

Kratom Acetaminophen And Codeine Capital® & Codeine Explained Increased CYP3A substrate exposure, increased risk of CNS depression and serotonin syndrome Details Kratom Amitriptyline Elavil Explained An increased risk of serotonin syndrome Details Kratom Sertraline Explained Increased CYP3A substrate exposure and increased risk of serotonin syndrome Details Kratom Buprenorphine Belbuca Explained Increased CYP3A substrate exposure, increased risk of CNS depression and serotonin syndrome Details Kratom Aripiprazole Injection Abilify Increased CYP3A substrate exposure and an increased risk of CNS depression Details Kratom Asenapine Transdermal Patch Secuado An increased risk of CNS depression Details Kratom Butorphanol Injection Butorphic Increased risk of CNS depression and serotonin syndrome Details Kratom Butorphanol Nasal Spray Stadol® NS Increased risk of CNS depression and serotonin syndrome Details Kratom Cetirizine Injection Aller-Tec An increased risk of CNS depression Details Kratom Cetirizine Ophthalmic Zerviate An increased risk of CNS depression Details Kratom Diazepam Nasal Spray Valtoco Increased CYP3A substrate exposure and an increased risk of CNS depression Details Kratom Diazepam Rectal Diastat Increased CYP3A substrate exposure and an increased risk of CNS depression Details Kratom Diphenhydramine Injection Banophen An increased risk of CNS depression Details Kratom Diphenhydramine Topical Afterbite with Antihistamine An increased risk of CNS depression Details Kratom Dolasetron Anzemet An increased risk of serotonin syndrome Details Kratom Dolasetron Injection Anzemet An increased risk of serotonin syndrome Details Kratom Esketamine Nasal Spray Spravato An increased risk of CNS depression Details Kratom Fentanyl Transdermal Patch Duragesic® Increased CYP3A substrate exposure, increased risk of CNS depression and serotonin syndrome Details Kratom Granisetron Transdermal Patch Sancuso An increased risk of serotonin syndrome Details Kratom Granisetron Injection Granisol An increased risk of serotonin syndrome Details Kratom Hydromorphone Injection Dilaudid Increased risk of CNS depression and serotonin syndrome Details Kratom Hydromorphone Rectal available generically Increased risk of CNS depression and serotonin syndrome Details Kratom Linezolid Injection Zyvox An increased risk of serotonin syndrome Details Kratom Lithium Carbonate Lithobid An increased risk of serotonin syndrome Details Kratom Midazolam Nasal Spray Nayzilam Increased CYP3A substrate exposure and an increased risk of CNS depression Details Kratom Midazolam Injection Nayzilam Increased CYP3A substrate exposure and an increased risk of CNS depression Details Kratom Morphine Injection Astramorph® PF Increased risk of CNS depression and serotonin syndrome Details Kratom Nalbuphine Injection Nubain® Increased risk of CNS depression and serotonin syndrome Details Kratom Palonosetron Injection Aloxi® An increased risk of serotonin syndrome Details

Moderate

Kratom Clindamycin ANTIROBE Explained Increased CYP3A substrate exposure Details Kratom Omeprazole Gastrobim Explained Increased CYP3A substrate exposure Details Kratom Colchicine Colcrys Explained Increased CYP3A substrate exposure Details Kratom Simvastatin Flolipid Explained Increased CYP3A substrate exposure Details Kratom Abemaciclib Verzenio Explained Increased CYP3A substrate exposure Details Kratom Acalabrutinib Calquence Increased CYP3A substrate exposure Details Kratom Alpelisib Piqray Increased CYP3A substrate exposure Details Kratom Apixaban Eliquis Explained Increased CYP3A substrate exposure Details Kratom Apremilast Otezla Increased CYP3A substrate exposure Details Kratom Asciminib Scemblix Increased CYP3A substrate exposure Details Kratom Atogepant Qulipta Increased CYP3A substrate exposure Details