Opipramol
48 interactions 4 explained in plain English
Medically reviewed by
Dr. Brian Staiger, PharmD, BCPS
· Updated Jul 4, 2026
· Editorial policy
· Data sources
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Most serious with:
Metoclopramide Nasal Spray
Linezolid Injection
Metoclopramide Injection
Granisetron Injection
Palonosetron Injection
Etodolac
Contraindicated
Opipramol Linezolid Injection Zyvox Neurotoxicity, seizures, or serotonin syndrome (hypertension, hyperthermia, myoclonus, mental status changes) Details Opipramol Metoclopramide Injection Gimoti An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Opipramol Metoclopramide Nasal Spray Gimoti An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome DetailsMajor
Opipramol Acetaminophen And Codeine Capital® & Codeine Explained Increased risk of serotonin syndrome Details Opipramol Sertraline Explained An increased risk of serotonin syndrome Details Opipramol Albuterol Oral Inhalation Accuneb® Explained An increased risk of cardiovascular system effects Details Opipramol Buprenorphine Belbuca Explained An increased risk of serotonin syndrome Details Opipramol Aspirin Acuprin® An increased risk of bleeding Details Opipramol Aspirin Rectal Aspirin An increased risk of bleeding Details Opipramol Bromfenac Ophthalmic Bromday® An increased risk of bleeding Details Opipramol Butorphanol Injection Butorphic Increased risk of serotonin syndrome Details Opipramol Butorphanol Nasal Spray Stadol® NS Increased risk of serotonin syndrome Details Opipramol Clonidine Transdermal Patch Catapres An increased risk of high blood pressure and may counteract the hypotensive effects of cloNIDine Details Opipramol Diclofenac Ophthalmic Voltaren® Eye Drops An increased risk of bleeding Details Opipramol Diclofenac Topical (Actinic Keratosis) Pennsaid An increased risk of bleeding Details Opipramol Diclofenac Topical (Arthritis Pain) Pennsaid® An increased risk of bleeding Details Opipramol Diclofenac Transdermal Patch Flector An increased risk of bleeding Details Opipramol Dolasetron Anzemet Increased risk of serotonin syndrome Details Opipramol Dolasetron Injection Anzemet Increased risk of serotonin syndrome Details Opipramol Etodolac Lodine An increased risk of bleeding Details Opipramol Fenoprofen Fenopron An increased risk of bleeding Details Opipramol Fentanyl Transdermal Patch Duragesic® Increased risk of serotonin syndrome Details Opipramol Flurbiprofen Ansaid An increased risk of bleeding Details Opipramol Flurbiprofen Ophthalmic Ocufen An increased risk of bleeding Details Opipramol Gatifloxacin Ophthalmic Zymar® An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Opipramol Granisetron Transdermal Patch Sancuso Increased risk of serotonin syndrome Details Opipramol Granisetron Injection Granisol Increased risk of serotonin syndrome Details Opipramol Hydromorphone Injection Dilaudid Increased risk of serotonin syndrome Details Opipramol Hydromorphone Rectal available generically Increased risk of serotonin syndrome Details Opipramol Hydroxychloroquine Plaquenil An increased risk of seizures Details Opipramol Ibuprofen Addaprin An increased risk of bleeding Details Opipramol Ketoprofen Actron® An increased risk of bleeding Details Opipramol Ketorolac Acular An increased risk of bleeding Details Opipramol Ketorolac Injection Acular An increased risk of bleeding Details Opipramol Ketorolac Nasal Spray Sprix An increased risk of bleeding Details Opipramol Ketorolac Ophthalmic Acular An increased risk of bleeding Details Opipramol Lithium Carbonate Lithobid Increased risk of serotonin syndrome Details Opipramol Meclofenamate Meclodium® An increased risk of bleeding Details Opipramol Mefenamic Acid Ponstel® An increased risk of bleeding Details Opipramol Meloxicam Alloxate An increased risk of bleeding DetailsNo interactions on this page match that filter — try the next page or clear the filter.
Check another drug
Still have questions about this combination?
Every question gets a real answer from a licensed pharmacist — free, and usually within a day.
Ask the pharmacistEducational information only, not medical advice. Always confirm interactions with your pharmacist
or prescriber before making any change to your medications.