Kava

29 interactions 1 explained in plain English
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Linezolid Injection
1 Major 28 Moderate
All (29) Major (1) Moderate (28)

Major

Kava Linezolid Injection Zyvox Increased risk of adverse effects from excessive monoamine oxidase inhibition Details

Moderate

Kava Acetaminophen And Codeine Capital® & Codeine Explained Increased central nervous system depression Details Kava Aspirin Acuprin® Increased risk of bleeding Details Kava Aspirin Rectal Aspirin Increased risk of bleeding Details Kava Anagrelide Agrylin Increased risk of bleeding Details Kava Becaplermin Topical Regranex Increased risk of bleeding Details Kava Clopidogrel Plavix Increased risk of bleeding Details Kava Dalteparin Injection Fragmin Increased risk of bleeding Details Kava Defibrotide Injection Defitelio Increased risk of bleeding Details Kava Diazepam Nasal Spray Valtoco Increased central nervous system depression Details Kava Diazepam Rectal Diastat Increased central nervous system depression Details Kava Dipyridamole Permole® Increased risk of bleeding Details Kava Enoxaparin Lovenox Increased risk of bleeding Details Kava Enoxaparin Injection Lovenox Increased risk of bleeding Details Kava Epoprostenol Flolan Increased risk of bleeding Details Kava Fentanyl Transdermal Patch Duragesic® Increased central nervous system depression Details Kava Fondaparinux Arixtra Increased risk of bleeding Details Kava Fondaparinux Injection Arixtra Increased risk of bleeding Details Kava Heparin Increased risk of bleeding Details Kava Heparin Injection Lipo-Hepin® Increased risk of bleeding Details Kava Hydromorphone Injection Dilaudid Increased central nervous system depression Details Kava Hydromorphone Rectal available generically Increased central nervous system depression Details Kava Iloprost Aurlumyn Increased risk of bleeding Details Kava Levodopa Oral Inhalation Inbrija Decreased effectiveness of levodopa Details Kava Metoclopramide Injection Gimoti Additive DOPamine antagonist effects Details Kava Metoclopramide Nasal Spray Gimoti Additive DOPamine antagonist effects Details Kava Midazolam Nasal Spray Nayzilam Increased central nervous system depression Details Kava Midazolam Injection Nayzilam Increased central nervous system depression Details Kava Morphine Injection Astramorph® PF Increased central nervous system depression Details

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