Halothane
38 interactions 3 explained in plain English
Medically reviewed by
Dr. Brian Staiger, PharmD, BCPS
· Updated Jul 4, 2026
· Editorial policy
· Data sources
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Most serious with:
Cetirizine Injection
Octreotide Injection
Metoclopramide Injection
Dolasetron Injection
Arsenic Trioxide Injection
Esketamine Nasal Spray
Major
Halothane Acetaminophen And Codeine Capital® & Codeine Explained An increased risk of respiratory and CNS depression Details Halothane Amitriptyline Elavil Explained An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Halothane Buprenorphine Belbuca Explained An increased risk of respiratory depression and CNS depression Details Halothane Arsenic Trioxide Trisenox An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Halothane Arsenic Trioxide Injection Trisenox An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Halothane Butorphanol Injection Butorphic Increased risk of respiratory and CNS depression Details Halothane Butorphanol Nasal Spray Stadol® NS Increased risk of respiratory and CNS depression Details Halothane Cetirizine Injection Aller-Tec Increased risk of CNS depression Details Halothane Cetirizine Ophthalmic Zerviate Increased risk of CNS depression Details Halothane Chloroquine Aralen® An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Halothane Diazepam Nasal Spray Valtoco Increased risk of CNS depression Details Halothane Diazepam Rectal Diastat Increased risk of CNS depression Details Halothane Disopyramide Norpace An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Halothane Dofetilide Tikosyn An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Halothane Dolasetron Anzemet An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Halothane Dolasetron Injection Anzemet An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Halothane Esketamine Nasal Spray Spravato Increased risk of sedation Details Halothane Fentanyl Transdermal Patch Duragesic® Increased risk of profound sedation, respiratory depression, hypotension, coma and death Details Halothane Flecainide Tambocor® An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Halothane Foscarnet Injection Foscavir An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Halothane Hydromorphone Injection Dilaudid Increased risk of respiratory and CNS depression Details Halothane Hydromorphone Rectal available generically Increased risk of respiratory and CNS depression Details Halothane Isradipine DynaCirc® An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Halothane Labetalol Normodyne® Hypotension or decreased cardiac output Details Halothane Lacosamide Injection Motpoly An increased risk of CNS depression Details Halothane Levodopa Oral Inhalation Inbrija An increased risk of CNS depression Details Halothane Mefloquine Lariam® An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Halothane Methylphenidate Adhansia XR® Increased risk of sudden blood pressure and heart rate increases Details Halothane Methylphenidate Transdermal Patch Daytrana Increased risk of sudden blood pressure and heart rate increases Details Halothane Metoclopramide Injection Gimoti Increased risk of CNS depression Details Halothane Metoclopramide Nasal Spray Gimoti Increased risk of CNS depression Details Halothane Morphine Injection Astramorph® PF Increased risk of profound sedation, respiratory depression, hypotension, coma and death Details Halothane Nalbuphine Injection Nubain® Increased risk of respiratory and CNS depression Details Halothane Octreotide Bynfezia An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Halothane Octreotide Injection Bynfezia An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) DetailsModerate
Halothane Clonidine Transdermal Patch Catapres An increased risk of sedation and somnolence Details Halothane Midazolam Nasal Spray Nayzilam Potentiation of anesthetic effects of halothane Details Halothane Midazolam Injection Nayzilam Potentiation of anesthetic effects of halothane DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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