Piritramide

29 interactions 3 explained in plain English
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Major

Piritramide Acetaminophen And Codeine Capital® & Codeine Explained Increased risk of respiratory and CNS depression and an increased risk of serotonin syndrome Details Piritramide Sertraline Explained An increased risk of serotonin syndrome Details Piritramide Buprenorphine Belbuca Explained An increased risk of serotonin syndrome and an increased risk of respiratory and CNS depression Details Piritramide Butorphanol Injection Butorphic Increased risk of serotonin syndrome; increased risk of respiratory and CNS depression Details Piritramide Butorphanol Nasal Spray Stadol® NS Increased risk of serotonin syndrome; increased risk of respiratory and CNS depression Details Piritramide Cetirizine Injection Aller-Tec Increased risk of CNS depression Details Piritramide Cetirizine Ophthalmic Zerviate Increased risk of CNS depression Details Piritramide Clopidogrel Plavix Reduced efficacy of clopidogrel Details Piritramide Diazepam Nasal Spray Valtoco Increased risk of profound sedation, respiratory and CNS depression, coma and death Details Piritramide Diazepam Rectal Diastat Increased risk of profound sedation, respiratory and CNS depression, coma and death Details Piritramide Esketamine Nasal Spray Spravato Increased risk of sedation Details Piritramide Fentanyl Transdermal Patch Duragesic® Increased risk of respiratory and CNS depression and an increased risk of serotonin syndrome Details Piritramide Granisetron Transdermal Patch Sancuso Increased risk of serotonin syndrome Details Piritramide Granisetron Injection Granisol Increased risk of serotonin syndrome Details Piritramide Hydromorphone Injection Dilaudid Increased risk of respiratory and CNS depression and an increased risk of serotonin syndrome Details Piritramide Hydromorphone Rectal available generically Increased risk of respiratory and CNS depression and an increased risk of serotonin syndrome Details Piritramide Lacosamide Injection Motpoly An increased risk of CNS depression Details Piritramide Levodopa Oral Inhalation Inbrija An increased risk of CNS depression Details Piritramide Linezolid Injection Zyvox An increased risk of serotonin syndrome Details Piritramide Lithium Carbonate Lithobid Increased risk of serotonin syndrome Details Piritramide Metoclopramide Injection Gimoti Increased risk of CNS depression Details Piritramide Metoclopramide Nasal Spray Gimoti Increased risk of CNS depression Details Piritramide Midazolam Nasal Spray Nayzilam Increased risk of hypoventilation, airway obstruction, desaturation, or apnea Details Piritramide Midazolam Injection Nayzilam Increased risk of hypoventilation, airway obstruction, desaturation, or apnea Details Piritramide Morphine Injection Astramorph® PF Increased risk of respiratory and CNS depression and an increased risk of serotonin syndrome Details Piritramide Nalbuphine Injection Nubain® Increased risk of serotonin syndrome; increased risk of respiratory and CNS depression Details Piritramide Palonosetron Injection Aloxi® An increased risk of serotonin syndrome Details

Check another drug

Still have questions about this combination?

Every question gets a real answer from a licensed pharmacist — free, and usually within a day.

Ask the pharmacist
Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.