Vildagliptin

19 interactions 1 explained in plain English
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 11, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Chloroquine Furosemide Injection Octreotide Injection Insulin Detemir (Rdna Origin) Injection Insulin Glulisine (Rdna Origin) Injection Lanreotide Injection
8 Major 11 Moderate
All (19) Major (8) Moderate (11)

Major

Vildagliptin Chloroquine Aralen® Hypoglycemia Details Vildagliptin Furosemide Injection Disal An increased risk of hyperglycemia and an increased insulin requirement Details Vildagliptin Insulin Degludec (Rdna Origin) Injection Ryzodeg® (as a combination product containing Insulin Degludec and Insulin Aspart) An increased risk of hypoglycemia Details Vildagliptin Insulin Detemir (Rdna Origin) Injection Levemir An increased risk of hypoglycemia Details Vildagliptin Insulin Glulisine (Rdna Origin) Injection Apidra An increased risk of hypoglycemia Details Vildagliptin Lanreotide Injection Somatuline An increased risk of hypoglycemia and impaired glucose regulation Details Vildagliptin Octreotide Bynfezia An increased risk of hypoglycemia and impaired glucose regulation Details Vildagliptin Octreotide Injection Bynfezia An increased risk of hypoglycemia and impaired glucose regulation Details

Moderate

Vildagliptin Atenolol Tenormin Explained Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Vildagliptin Acebutolol Sectral® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Vildagliptin Betaxolol Betoptic S Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Vildagliptin Betaxolol Ophthalmic Betoptic® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Vildagliptin Bisoprolol Zebeta® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Vildagliptin Esmolol Brevibloc Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Vildagliptin Labetalol Normodyne® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Vildagliptin Levobunolol Ophthalmic AKBeta® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Vildagliptin Nadolol Corgard Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Vildagliptin Nebivolol Bystolic Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Vildagliptin Penbutolol Levatol® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.