Canrenone

Name: Canrenone Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

11 interactions 2 explained in plain English

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Acetaminophen And Codeine Buprenorphine Arsenic Trioxide Arsenic Trioxide Injection Cyclosporine Injection Cyclosporine Ophthalmic

10 Major 1 Moderate

All (11) Major (10) Moderate (1)

Major

Canrenone Acetaminophen And Codeine Capital® & Codeine Explained Reduced diuretic efficacy Details Canrenone Buprenorphine Belbuca Explained Reduced efficacy of diuretics Details Canrenone Arsenic Trioxide Trisenox Increased risk of QT-interval prolongation and torsade de pointes Details Canrenone Arsenic Trioxide Injection Trisenox Increased risk of QT-interval prolongation and torsade de pointes Details Canrenone Cyclosporine Injection Atopica An increased risk of hyperkalemia Details Canrenone Cyclosporine Ophthalmic Cequa An increased risk of hyperkalemia Details Canrenone Fentanyl Transdermal Patch Duragesic® Reduced diuretic efficacy Details Canrenone Hydromorphone Injection Dilaudid Reduced efficacy of diuretics Details Canrenone Hydromorphone Rectal available generically Reduced efficacy of diuretics Details Canrenone Morphine Injection Astramorph® PF Reduced efficacy of diuretics Details

Moderate

Canrenone Metformin Fortamet® An increased risk of hyperglycemia and potential loss of glycemic control Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.