Ethacrynic Acid
57 interactions 4 explained in plain English
Also sold as:
Edecrin
Medically reviewed by
Dr. Brian Staiger, PharmD, BCPS
· Updated Jul 4, 2026
· Editorial policy
· Data sources
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Most serious with:
Desmopressin Nasal
Naproxen
Ketorolac Nasal Spray
Ketoprofen
Amikacin Oral Inhalation
Flurbiprofen
Contraindicated
Ethacrynic Acid Desmopressin Nasal Concentraid® Increased risk of severe hyponatremia DetailsMajor
Ethacrynic Acid Acetaminophen And Codeine Capital® & Codeine Explained Reduced diuretic efficacy Details Ethacrynic Acid Albuterol Oral Inhalation Accuneb® Explained An increased risk of ECG changes or hypokalemia Details Ethacrynic Acid Buprenorphine Belbuca Explained Reduced efficacy of diuretics Details Ethacrynic Acid Amikacin Injection Amikin® Increased amikacin plasma and tissue concentrations and additive ototoxicity Details Ethacrynic Acid Amikacin Oral Inhalation Arikayce Increased amikacin plasma and tissue concentrations and additive ototoxicity Details Ethacrynic Acid Arsenic Trioxide Trisenox Increased risk of QT-interval prolongation and torsade de pointes Details Ethacrynic Acid Arsenic Trioxide Injection Trisenox Increased risk of QT-interval prolongation and torsade de pointes Details Ethacrynic Acid Aspirin Acuprin® Reduced diuretic effectiveness and possible nephrotoxicity Details Ethacrynic Acid Aspirin Rectal Aspirin Reduced diuretic effectiveness and possible nephrotoxicity Details Ethacrynic Acid Bromfenac Ophthalmic Bromday® Reduced diuretic effectiveness and possible nephrotoxicity Details Ethacrynic Acid Cefepime Injection Maxipime® An increased risk of nephrotoxicity Details Ethacrynic Acid Diclofenac Ophthalmic Voltaren® Eye Drops Reduced diuretic effectiveness and possible nephrotoxicity Details Ethacrynic Acid Diclofenac Topical (Actinic Keratosis) Pennsaid Reduced diuretic effectiveness and possible nephrotoxicity Details Ethacrynic Acid Diclofenac Topical (Arthritis Pain) Pennsaid® Reduced diuretic effectiveness and possible nephrotoxicity Details Ethacrynic Acid Diclofenac Transdermal Patch Flector Reduced diuretic effectiveness and possible nephrotoxicity Details Ethacrynic Acid Etodolac Lodine Reduced diuretic effectiveness and possible nephrotoxicity Details Ethacrynic Acid Fenoprofen Fenopron Reduced diuretic effectiveness and possible nephrotoxicity Details Ethacrynic Acid Fentanyl Transdermal Patch Duragesic® Reduced diuretic efficacy Details Ethacrynic Acid Flurbiprofen Ansaid Reduced diuretic effectiveness and possible nephrotoxicity Details Ethacrynic Acid Flurbiprofen Ophthalmic Ocufen Reduced diuretic effectiveness and possible nephrotoxicity Details Ethacrynic Acid Foscarnet Injection Foscavir Impaired foscarnet elimination and potential for toxicity Details Ethacrynic Acid Furosemide Injection Disal An increased risk of ototoxicity Details Ethacrynic Acid Gentamicin Injection Garamycin® I.V. Increased gentamicin plasma and tissue concentrations and additive ototoxicity Details Ethacrynic Acid Gentamicin Ophthalmic Garamycin® Ophthalmic Increased gentamicin plasma and tissue concentrations and additive ototoxicity Details Ethacrynic Acid Gentamicin Topical Garamycin® Increased gentamicin plasma and tissue concentrations and additive ototoxicity Details Ethacrynic Acid Hydromorphone Injection Dilaudid Reduced efficacy of diuretics Details Ethacrynic Acid Hydromorphone Rectal available generically Reduced efficacy of diuretics Details Ethacrynic Acid Ibuprofen Addaprin Reduced diuretic effectiveness and possible nephrotoxicity Details Ethacrynic Acid Ketoprofen Actron® Reduced diuretic effectiveness and possible nephrotoxicity Details Ethacrynic Acid Ketorolac Acular Reduced diuretic effectiveness and possible nephrotoxicity Details Ethacrynic Acid Ketorolac Injection Acular Reduced diuretic effectiveness and possible nephrotoxicity Details Ethacrynic Acid Ketorolac Nasal Spray Sprix Reduced diuretic effectiveness and possible nephrotoxicity Details Ethacrynic Acid Ketorolac Ophthalmic Acular Reduced diuretic effectiveness and possible nephrotoxicity Details Ethacrynic Acid Lithium Carbonate Lithobid An increased risk of lithium toxicity Details Ethacrynic Acid Meclofenamate Meclodium® Reduced diuretic effectiveness and possible nephrotoxicity Details Ethacrynic Acid Mefenamic Acid Ponstel® Reduced diuretic effectiveness and possible nephrotoxicity Details Ethacrynic Acid Meloxicam Alloxate Reduced diuretic effectiveness and possible nephrotoxicity Details Ethacrynic Acid Meloxicam Injection Alloxate Reduced diuretic effectiveness and possible nephrotoxicity Details Ethacrynic Acid Morphine Injection Astramorph® PF Reduced efficacy of diuretics DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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