Amikacin Injection

75 interactions 361 cited references
Also sold as: Amikin® Arikayce
About Amikacin Injection

Amikacin injection is used to treat certain serious infections that are caused by bacteria such as meningitis (infection of the membranes that surround the brain and spinal cord) and infections of the blood, abdomen (stomach area), lungs, skin, bones, joints, and urinary tract. Amikacin injection is in a class of medic… Read the full Amikacin Injection drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 12, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Major

Amikacin Injection Alcuronium Enhanced and/or prolonged neuromuscular blockade which may lead to respiratory depression and paralysis Details Amikacin Injection Aspirin Acuprin® Increased aspirin exposure and an increased risk of nephrotoxicity Details Amikacin Injection Atracurium Enhanced and/or prolonged neuromuscular blockade which may lead to respiratory depression and paralysis Details Amikacin Injection Bumetanide Bumex An increased risk of ototoxicity Details Amikacin Injection Cefepime An increased risk of nephrotoxicity and an increased risk of ototoxicity Details Amikacin Injection Cholera Vaccine, Live Reduced immune response to the cholera vaccine Details Amikacin Injection Cidofovir Nephrotoxicity Details Amikacin Injection Cisatracurium Enhanced and/or prolonged neuromuscular blockade which may lead to respiratory depression and paralysis Details Amikacin Injection Colistimethate Sodium Respiratory depression Details Amikacin Injection Decamethonium Enhanced and/or prolonged neuromuscular blockade which may lead to respiratory depression and paralysis Details Amikacin Injection Doxacurium Enhanced and/or prolonged neuromuscular blockade which may lead to respiratory depression and paralysis Details Amikacin Injection Emtricitabine Emtriva Increased emtricitabine exposure and an increased risk of emtricitabine-related adverse effects Details Amikacin Injection Ethacrynic Acid Edecrin Increased amikacin plasma and tissue concentrations and additive ototoxicity Details Amikacin Injection Fazadinium Enhanced and/or prolonged neuromuscular blockade which may lead to respiratory depression and paralysis Details Amikacin Injection Foscarnet Foscavir Nephrotoxicity Details Amikacin Injection Furosemide Disal Increased amikacin exposure and an increased risk of ototoxicity and/or nephrotoxicity Details Amikacin Injection Gallamine Enhanced and/or prolonged neuromuscular blockade which may lead to respiratory depression and paralysis Details Amikacin Injection Hexafluorenium Enhanced and/or prolonged neuromuscular blockade which may lead to respiratory depression and paralysis Details Amikacin Injection Letibotulinumtoxina-Wlbg Letybo Increased neuromuscular weakness Details Amikacin Injection Lysine Increased risk of nephrotoxicity Details Amikacin Injection Mannitol Alteration of serum and tissue amikacin concentrations Details Amikacin Injection Metocurine Enhanced and/or prolonged neuromuscular blockade which may lead to respiratory depression and paralysis Details Amikacin Injection Mivacurium Enhanced and/or prolonged neuromuscular blockade which may lead to respiratory depression and paralysis Details Amikacin Injection Pancuronium Enhanced and/or prolonged neuromuscular blockade which may lead to respiratory depression and paralysis Details Amikacin Injection Pipecuronium Enhanced and/or prolonged neuromuscular blockade which may lead to respiratory depression and paralysis Details Amikacin Injection Rapacuronium Enhanced and/or prolonged neuromuscular blockade which may lead to respiratory depression and paralysis Details Amikacin Injection Rocuronium Enhanced and/or prolonged neuromuscular blockade which may lead to respiratory depression and paralysis Details Amikacin Injection Succinylcholine Anectine Succinylcholine toxicity (respiratory depression) Details Amikacin Injection Tacrolimus Astagraf An increased risk of nephrotoxicity Details Amikacin Injection Teicoplanin Increased risk of nephrotoxicity and/or ototoxicity Details Amikacin Injection Tenofovir Alafenamide Increased tenofovir alafenamide exposure and an increased risk of tenofovir alafenamide-related adverse effects Details Amikacin Injection Tubocurarine Enhanced and/or prolonged neuromuscular blockade which may lead to respiratory depression and paralysis Details Amikacin Injection Urea Atrac-Tain Alteration of serum and tissue amikacin concentrations Details Amikacin Injection Vancomycin Firvanq An increased risk of ototoxicity and/or an increased risk of nephrotoxicity Details Amikacin Injection Vecuronium Enhanced and/or prolonged neuromuscular blockade which may lead to respiratory depression and paralysis Details

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