Enalapril
198 interactions 937 cited referencesEnalapril is an ACE inhibitor used to treat high blood pressure and heart failure. Read the full Enalapril drug information page →
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Contraindicated
Enalapril Aliskiren Tekturna An increased risk of hyperkalemia, renal impairment, and hypotension Details Enalapril Sacubitril Increased risk of angioedema Details Enalapril Valsartan Diovan Increased risk of angioedema and an increased risk of adverse events (ie, hypotension, syncope, hyperkalemia, changes in renal fun... DetailsMajor
Enalapril Allopurinol Aloprim Hypersensitivity reactions (Stevens-Johnson syndrome, skin eruptions, anaphylactic coronary spasm) Details Enalapril Allopurinol Injection Aloprim Hypersensitivity reactions (Stevens-Johnson syndrome, skin eruptions, anaphylactic coronary spasm) Details Enalapril Aspirin Acuprin® Reduced hyponatremic and hypotensive effects of ACE inhibitors Details Enalapril Aspirin Rectal Aspirin Reduced hyponatremic and hypotensive effects of ACE inhibitors Details Enalapril Azathioprine Azasan An increased risk of myelosuppression and an increased risk of hepatotoxicity Details Enalapril Azilsartan Edarbi Increased risk of adverse events (ie, hypotension, syncope, hyperkalemia, changes in renal function, acute renal failure) Details Enalapril Digoxin Cardoxin® An increased digoxin exposure Details Enalapril Alteplase, Recombinant Activase An increased risk of orolingual angioedema Details Enalapril Amiloride Increased risk of hyperkalemia Details Enalapril Azilsartan Medoxomil Edarbi Increased risk of adverse events (ie, hypotension, syncope, hyperkalemia, changes in renal function, acute renal failure) Details Enalapril Candesartan Atacand Increased risk of adverse events (ie, hypotension, syncope, hyperkalemia, changes in renal function, acute renal failure) Details Enalapril Canrenoate Increased risk of hyperkalemia Details Enalapril Cyclosporine Atopica Acute renal dysfunction and an increased risk of hyperkalemia Details Enalapril Eplerenone Inspra Increased risk of hyperkalemia Details Enalapril Eprosartan Teveten® Increased risk of adverse events (ie, hypotension, syncope, hyperkalemia, changes in renal function, acute renal failure) Details Enalapril Everolimus Afinitor Increased risk of angioedema Details Enalapril Furosemide Disal An increased risk of severe hypotension and deterioration in renal function, including renal failure Details Enalapril Insulin Icodec-Abae Awiqli An increased risk of hypoglycemia Details Enalapril Interferon Alfa-2A Hematologic abnormalities (granulocytopenia, thrombocytopenia) Details Enalapril Irbesartan Avapro Increased risk of adverse events (ie, hypotension, syncope, hyperkalemia, changes in renal function, acute renal failure) Details Enalapril Levoketoconazole Recorlev Increased risk of serious hepatotoxicity and drug-induced liver injury Details Enalapril Lithium Increased risk of lithium toxicity Details Enalapril Losartan Arbli Increased risk of adverse events (ie, hypotension, syncope, hyperkalemia, changes in renal function, acute renal failure) Details Enalapril Melphalan Alkeran An increased risk of severe hypotension Details Enalapril Mercaptopurine Purinethol® An increased risk of myelosuppression and an increased risk of hepatotoxicity Details Enalapril Methotrexate Jylamvo Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Enalapril Olmesartan Benicar Increased risk of adverse events (ie, hypotension, syncope, hyperkalemia, changes in renal function, acute renal failure) Details Enalapril Oxypurinol Hypersensitivity reactions (Stevens-Johnson syndrome, skin eruptions, anaphylactic coronary spasm) Details Enalapril Potassium Citrate Urocit-K Increased risk of hyperkalemia Details Enalapril Potassium Phosphate K-Phos Increased risk of severe and potentially fatal hyperkalemia Details Enalapril Pregabalin Bonqat Increased risk of angioedema Details Enalapril Rifampin Rifadin Reduced enalapril active metabolite exposure Details Enalapril Sirolimus Felycin Increased risk of angioedema Details Enalapril Spironolactone Aldactone Increased risk of hyperkalemia Details Enalapril Tacrolimus Astagraf An increased risk of hyperkalemia Details Enalapril Telmisartan Micardis Increased risk of adverse events (ie, hypotension, syncope, hyperkalemia, changes in renal function, acute renal failure) Details Enalapril Temsirolimus Torisel Increased risk of angioedema DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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