Infigratinib

118 interactions 43 cited references

Also sold as: Truseltiq Truseltiq®

About Infigratinib

Infigratinib is used in adults who have received previous therapy to treat a certain type of cholangiocarcinoma (bile duct cancer) that has spread to nearby tissues or other parts of the body and cannot be removed by surgery. Infigratinib is in a class of medications called kinase inhibitors. It works by blocking the a… Read the full Infigratinib drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Rubella Virus Vaccine, Live Measles Virus Vaccine, Live Bacillus Of Calmette And Guerin Vaccine, Live Ensitrelvir Mumps Virus Vaccine, Live Dengue Tetravalent Vaccine, Live

10 Contraindicated 104 Major 4 Moderate

All (118) Contraindicated (10) Major (104) Moderate (4)

Contraindicated

Infigratinib Bacillus Of Calmette And Guerin Vaccine, Live An increased risk of infection by the live vaccine Details Infigratinib Dengue Tetravalent Vaccine, Live An increased risk of infection by the live vaccine Details Infigratinib Ensitrelvir Increased CYP3A substrates exposure and an increased risk of CYP3A substrates-related adverse effects Details Infigratinib Measles Virus Vaccine, Live An increased risk of infection by the live vaccine Details Infigratinib Mumps Virus Vaccine, Live An increased risk of infection by the live vaccine Details Infigratinib Rubella Virus Vaccine, Live An increased risk of infection by the live vaccine Details Infigratinib Smallpox Monkeypox Vaccine An increased risk of infection by the live vaccine Details Infigratinib Typhoid Vaccine Typhim VI® An increased risk of infection by the live vaccine Details Infigratinib Varicella Virus Vaccine, Live An increased risk of infection by the live vaccine Details Infigratinib Yellow Fever Vaccine Stamaril An increased risk of infection by the live vaccine Details

Major

Infigratinib Omeprazole Gastrobim Decreased infigratinib plasma concentrations Details Infigratinib Cyclosporine Injection Atopica Increased infigratinib plasma concentrations Details Infigratinib Cyclosporine Ophthalmic Cequa Increased infigratinib plasma concentrations Details Infigratinib Dexlansoprazole Dexilant Decreased infigratinib plasma concentrations Details Infigratinib Esomeprazole Nexium Decreased infigratinib plasma concentrations Details Infigratinib Esomeprazole Injection Nexium Decreased infigratinib plasma concentrations Details Infigratinib Famotidine Calmicid Decreased infigratinib plasma concentrations Details Infigratinib Famotidine Injection Calmicid Decreased infigratinib plasma concentrations Details Infigratinib Adenovirus Vaccine Type 4, Live An increased risk of infection by the live vaccine Details Infigratinib Adenovirus Vaccine Type 7, Live An increased risk of infection by the live vaccine Details Infigratinib Aluminum Carbonate, Basic Decreased infigratinib plasma concentrations Details Infigratinib Aluminum Hydroxide AlternaGEL® Decreased infigratinib plasma concentrations Details Infigratinib Aluminum Phosphate Decreased infigratinib plasma concentrations Details Infigratinib Apalutamide Erleada Decreased infigratinib plasma concentrations Details Infigratinib Aprepitant Aponvie Increased infigratinib plasma concentrations Details Infigratinib Atazanavir Reyataz Increased infigratinib plasma concentrations Details Infigratinib Boceprevir Increased infigratinib plasma concentrations Details Infigratinib Bosentan Decreased infigratinib plasma concentrations Details Infigratinib Calcium Carbonate Alka-Mints Decreased infigratinib plasma concentrations Details Infigratinib Calcium Silicate Decreased infigratinib plasma concentrations Details Infigratinib Carbamazepine Carbatrol Decreased infigratinib plasma concentrations Details Infigratinib Cenobamate Xcopri Decreased infigratinib plasma concentrations Details Infigratinib Cholera Vaccine Ipol An increased risk of infection by the live vaccine Details Infigratinib Cimetidine Tagamet Decreased infigratinib plasma concentrations Details Infigratinib Ciprofloxacin Increased infigratinib plasma concentrations Details Infigratinib Clarithromycin Biaxin Increased infigratinib plasma concentrations Details Infigratinib Cobicistat Tybost Increased infigratinib plasma concentrations Details Infigratinib Conivaptan Vaprisol Increased infigratinib plasma concentrations Details Infigratinib Crizotinib Xalkori Increased infigratinib plasma concentrations Details Infigratinib Cyclosporine Atopica Increased infigratinib plasma concentrations Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.