Arsenic Trioxide Injection

282 interactions 448 cited references

Also sold as: Trisenox Trisenox®

About Arsenic Trioxide Injection

Arsenic trioxide is used in combination with tretinoin to treat acute promyelocytic leukemia (APL; a type of cancer in which there are too many immature blood cells in the blood and bone marrow) in certain people as a first treatment. It is also used to treat APL in certain people who have not been helped by other type… Read the full Arsenic Trioxide Injection drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 12, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Foscarnet Levoketoconazole Lidoflazine Measles Virus Vaccine, Live Mesoridazine Mumps Virus Vaccine, Live

23 Contraindicated 259 Major

All (282) Contraindicated (23) Major (259)

Contraindicated

Arsenic Trioxide Injection Bacillus Of Calmette And Guerin Vaccine, Live An increased risk of infection by the live vaccine Details Arsenic Trioxide Injection Bepridil An increased risk of QT interval prolongation Details Arsenic Trioxide Injection Cisapride Propulsid® Increased risk of QT interval prolongation Details Arsenic Trioxide Injection Dengue Tetravalent Vaccine, Live An increased risk of infection by the live vaccine Details Arsenic Trioxide Injection Dronedarone Multaq Increased risk of QT interval prolongation Details Arsenic Trioxide Injection Foscarnet Foscavir An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Arsenic Trioxide Injection Levoketoconazole Recorlev An increased risk of QT interval prolongation and an increased risk of torsade de pointes Details Arsenic Trioxide Injection Lidoflazine An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Arsenic Trioxide Injection Measles Virus Vaccine, Live An increased risk of infection by the live vaccine Details Arsenic Trioxide Injection Mesoridazine An increased risk of QT interval prolongation Details Arsenic Trioxide Injection Mumps Virus Vaccine, Live An increased risk of infection by the live vaccine Details Arsenic Trioxide Injection Pimozide An increased risk of QT interval prolongation Details Arsenic Trioxide Injection Piperaquine An increased risk of QT interval prolongation Details Arsenic Trioxide Injection Rubella Virus Vaccine, Live An increased risk of infection by the live vaccine Details Arsenic Trioxide Injection Saquinavir An increased risk of QT interval prolongation Details Arsenic Trioxide Injection Smallpox Monkeypox Vaccine An increased risk of infection by the live vaccine Details Arsenic Trioxide Injection Sparfloxacin An increased risk of QT interval prolongation Details Arsenic Trioxide Injection Terfenadine An increased risk of QT interval prolongation Details Arsenic Trioxide Injection Thioridazine An increased risk of QT interval prolongation Details Arsenic Trioxide Injection Typhoid Vaccine Typhim VI® An increased risk of infection by the live vaccine Details Arsenic Trioxide Injection Varicella Virus Vaccine, Live An increased risk of infection by the live vaccine Details Arsenic Trioxide Injection Yellow Fever Vaccine Stamaril An increased risk of infection by the live vaccine Details Arsenic Trioxide Injection Ziprasidone Geodon An increased risk of QT interval prolongation Details

Major

Arsenic Trioxide Injection Acecainide Cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Arsenic Trioxide Injection Acetazolamide Diamox® Sequels® Increased risk of QT-interval prolongation and torsade de pointes Details Arsenic Trioxide Injection Adagrasib Krazati An increased risk of QT interval prolongation, torsade de pointes, polymorphic ventricular tachycardia, other serious arrhythmias Details Arsenic Trioxide Injection Adenovirus Vaccine Type 4, Live An increased risk of infection by the live vaccine Details Arsenic Trioxide Injection Adenovirus Vaccine Type 7, Live An increased risk of infection by the live vaccine Details Arsenic Trioxide Injection Ajmaline An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Arsenic Trioxide Injection Alfuzosin UroXatral An increased risk of QT interval prolongation Details Arsenic Trioxide Injection Amiloride Increased risk of QT-interval prolongation and torsade de pointes Details Arsenic Trioxide Injection Amiodarone Nexterone Cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Arsenic Trioxide Injection Amisulpride Barhemsys Increased risk of serious ventricular arrhythmias such as torsades de pointes Details Arsenic Trioxide Injection Amitriptyline Elavil An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Arsenic Trioxide Injection Amoxapine An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Arsenic Trioxide Injection Amphotericin B Increased risk of QT prolongation Details Arsenic Trioxide Injection Anagrelide Agrylin Increased risk of QT interval prolongation Details Arsenic Trioxide Injection Apomorphine Apokyn An increased risk of QT interval prolongation Details Arsenic Trioxide Injection Aprindine An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Arsenic Trioxide Injection Aripiprazole Abilify An increased risk of QT interval prolongation Details

Check another drug

Still have questions about this combination?

Every question gets a real answer from a licensed pharmacist — free, and usually within a day.

Ask the pharmacist

Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.