Nimodipine

77 interactions 261 cited references
Also sold as: Nimotop Nimotop® Nymalize Nymalize®
About Nimodipine

Nimodipine is used to decrease brain damage that may be caused by a subarachnoid hemorrhage (bleeding in the space surrounding the brain that occurs when a weakened blood vessel in the brain bursts). Nimodipine is in a class of medications called calcium channel blockers. It works by relaxing blood vessels in the brain… Read the full Nimodipine drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Major

Nimodipine Clonidine Transdermal Patch Catapres An increased risk of worsen sinus node dysfunction and atrioventricular node conduction, an increased risk of bradycardia and AV b... Details Nimodipine Clopidogrel Plavix Decreased antiplatelet effect and increased risk of thrombotic events Details Nimodipine Dexamethasone Injection Decadron Reduced nimodipine plasma concentrations and reduced nimodipine efficacy Details Nimodipine Dexamethasone Ophthalmic Dexacidin® (as a combination product containing Dexamethasone, Neomycin, Polymyxin B) Reduced nimodipine plasma concentrations and reduced nimodipine efficacy Details Nimodipine Digoxin Cardoxin® An increased risk of bradycardia and an increased risk of complete heart block Details Nimodipine Epirubicin Ellence Increased risk of heart failure Details Nimodipine Lacosamide Injection Motpoly An increased risk of AV block, bradycardia, and ventricular tachyarrhythmia Details Nimodipine Melphalan Alkeran An increased risk of severe hypotension Details Nimodipine Melphalan Injection Alkeran An increased risk of severe hypotension Details Nimodipine Carbamazepine Carbatrol Reduced nimodipine plasma concentrations and reduced nimodipine efficacy Details Nimodipine Ceritinib Zykadia Increased CYP3A substrate exposure Details Nimodipine Clonidine Duraclon An increased risk of worsen sinus node dysfunction and atrioventricular node conduction, an increased risk of bradycardia and AV b... Details Nimodipine Cobicistat Tybost Increased risk of significant hypotension Details Nimodipine Dantrolene Dantrium Severe hyperkalemia with cardiovascular collapse Details Nimodipine Darunavir Increased calcium channel blocker exposure and an increased risk of calcium channel blocker-related adverse effects Details Nimodipine Dexamethasone Reduced nimodipine plasma concentrations and reduced nimodipine efficacy Details Nimodipine Fosphenytoin Cerebyx Reduced niMODipine exposure and reduced efficacy niMODipine efficacy Details Nimodipine Itraconazole Sporanox An increased risk of congestive heart failure Details Nimodipine Lacosamide Motpoly An increased risk of AV block, bradycardia, and ventricular tachyarrhythmia Details Nimodipine Landiolol An increased risk of myocardial contractility depression and increase the risk of bradycardia or heart block Details Nimodipine Phenobarbital Fidoquel Reduced nimodipine plasma concentrations and reduced nimodipine efficacy Details Nimodipine Phenytoin Dilantin Reduced niMODipine exposure and reduced efficacy niMODipine efficacy Details Nimodipine Ponesimod Ponvory An increased risk of bradycardia and heart block Details Nimodipine Rifampin Rifadin Reduced nimodipine plasma concentrations and reduced nimodipine efficacy Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.