Natalizumab Injection

Name: Natalizumab Injection Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

5 interactions 77 cited references

Also sold as: Tyruko Tysabri Tysabri®

About Natalizumab Injection

Natalizumab is used to prevent episodes of symptoms and slow the worsening of disability in adults who have relapsing forms of multiple sclerosis (MS; a disease in which the nerves do not function properly and people may experience weakness, numbness, loss of muscle coordination, and problems with vision, speech, and b… Read the full Natalizumab Injection drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Abatacept Anifrolumab-Fnia Certolizumab Pegol Infliximab Vedolizumab

5 Major

All (5) Major (5)

Major

Natalizumab Injection Abatacept Orencia An increased risk of infection Details Natalizumab Injection Anifrolumab-Fnia Saphnelo Additive effects due to duplication of therapy Details Natalizumab Injection Certolizumab Pegol An increased risk of serious infections Details Natalizumab Injection Infliximab Avsola Increased immunosuppression and an increased risk of infections Details Natalizumab Injection Vedolizumab An increased risk of progressive multifocal leukoencephalopathy (PML) and other infections Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.