Fenofibric Acid

16 interactions 2 explained in plain English
Also sold as: Fibricor Trilipix
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Colchicine Simvastatin Atorvastatin Cholestyramine Resin Colesevelam Colestipol
11 Major 5 Moderate
All (16) Major (11) Moderate (5)

Major

Fenofibric Acid Colchicine Colcrys Explained An increased risk of myopathy, including rhabdomyolysis Details Fenofibric Acid Simvastatin Flolipid Explained An increased risk of myopathy or rhabdomyolysis Details Fenofibric Acid Atorvastatin Atorvaliq An increased risk of myopathy or rhabdomyolysis Details Fenofibric Acid Cholestyramine Resin Locholest® Reduced absorption of fenofibrate Details Fenofibric Acid Colesevelam Welchol Reduced fenofibric acid effectiveness and reduced absorption of fenofibrate Details Fenofibric Acid Colestipol Colestid Reduced absorption of fenofibrate Details Fenofibric Acid Cyclosporine Injection Atopica An increased risk of nephrotoxicity with reduced creatine clearance and an increased risk of renal function deterioration Details Fenofibric Acid Cyclosporine Ophthalmic Cequa An increased risk of nephrotoxicity with reduced creatine clearance and an increased risk of renal function deterioration Details Fenofibric Acid Ezetimibe Zetia Increased ezetimibe exposure and an increased risk of cholelithiasis, myopathy and rhabdomyolysis Details Fenofibric Acid Fluvastatin Lescol An increased risk of myopathy and rhabdomyolysis Details Fenofibric Acid Lovastatin Altocor® An increased risk of myopathy or rhabdomyolysis Details

Moderate

Fenofibric Acid Bempedoic Acid Nexletol An increased triglycerides and reduced high-density lipoprotein cholesterol (HDL-C) Details Fenofibric Acid Glimepiride Amaryl Increased glimepiride exposure and increased blood glucose lowering effect and risk of hypoglycemia Details Fenofibric Acid Insulin Degludec (Rdna Origin) Injection Ryzodeg® (as a combination product containing Insulin Degludec and Insulin Aspart) An increased risk of hypoglycemia Details Fenofibric Acid Insulin Detemir (Rdna Origin) Injection Levemir An increased risk of hypoglycemia Details Fenofibric Acid Insulin Glulisine (Rdna Origin) Injection Apidra An increased risk of hypoglycemia Details

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