Difenoxin

Major

Difenoxin Acetaminophen And Codeine Capital® & Codeine Explained Increased risk of respiratory and CNS depression and an increased risk of serotonin syndrome Details Difenoxin Sertraline Explained An increased risk of serotonin syndrome Details Difenoxin Buprenorphine Belbuca Explained An increased risk of serotonin syndrome and an increased risk of respiratory and CNS depression Details Difenoxin Butorphanol Injection Butorphic Increased risk of serotonin syndrome; increased risk of respiratory and CNS depression Details Difenoxin Butorphanol Nasal Spray Stadol® NS Increased risk of serotonin syndrome; increased risk of respiratory and CNS depression Details Difenoxin Cetirizine Injection Aller-Tec Increased risk of CNS depression Details Difenoxin Cetirizine Ophthalmic Zerviate Increased risk of CNS depression Details Difenoxin Clopidogrel Plavix Reduced efficacy of clopidogrel Details Difenoxin Diazepam Nasal Spray Valtoco Increased risk of profound sedation, respiratory and CNS depression, coma and death Details Difenoxin Diazepam Rectal Diastat Increased risk of profound sedation, respiratory and CNS depression, coma and death Details Difenoxin Digoxin Cardoxin® Increased digoxin exposure Details Difenoxin Esketamine Nasal Spray Spravato Increased risk of sedation Details Difenoxin Fentanyl Transdermal Patch Duragesic® Increased risk of respiratory and CNS depression and an increased risk of serotonin syndrome Details Difenoxin Granisetron Transdermal Patch Sancuso Increased risk of serotonin syndrome Details Difenoxin Granisetron Injection Granisol Increased risk of serotonin syndrome Details Difenoxin Hydromorphone Injection Dilaudid Increased risk of respiratory and CNS depression and an increased risk of serotonin syndrome Details Difenoxin Hydromorphone Rectal available generically Increased risk of respiratory and CNS depression and an increased risk of serotonin syndrome Details Difenoxin Hydroxychloroquine Plaquenil An increased risk of seizures Details Difenoxin Lacosamide Injection Motpoly An increased risk of CNS depression Details Difenoxin Levodopa Oral Inhalation Inbrija An increased risk of CNS depression Details Difenoxin Linezolid Injection Zyvox An increased risk of hypertensive crisis (headache, hyperpyrexia, hypertension) Details Difenoxin Lithium Carbonate Lithobid Increased risk of serotonin syndrome Details Difenoxin Metoclopramide Injection Gimoti Increased risk of CNS depression Details Difenoxin Metoclopramide Nasal Spray Gimoti Increased risk of CNS depression Details Difenoxin Midazolam Nasal Spray Nayzilam Increased risk of hypoventilation, airway obstruction, desaturation, or apnea Details Difenoxin Midazolam Injection Nayzilam Increased risk of hypoventilation, airway obstruction, desaturation, or apnea Details Difenoxin Morphine Injection Astramorph® PF Increased risk of respiratory and CNS depression and an increased risk of serotonin syndrome Details Difenoxin Nalbuphine Injection Nubain® Increased risk of serotonin syndrome; increased risk of respiratory and CNS depression Details Difenoxin Palonosetron Injection Aloxi® An increased risk of serotonin syndrome Details

Moderate

Difenoxin Clonidine Transdermal Patch Catapres An increased risk of sedation and somnolence Details Difenoxin Desmopressin Nasal Concentraid® Increased risk of water intoxication with hyponatremia Details