Sotagliflozin

Contraindicated

Sotagliflozin Colchicine Colcrys Explained Increased colchicine exposure and an increased risk of colchicine toxicity Details

Major

Sotagliflozin Relugolix Orgovyx Explained Increased relugolix exposure Details Sotagliflozin Atogepant Qulipta Reduced atogepant exposure Details Sotagliflozin Cariprazine Vraylar Explained Effects on the cariprazine exposure has not been evaluated and the net effect is unclear Details Sotagliflozin Amlodipine Amvaz® Reduced amLODIPine exposure Details Sotagliflozin Dabigatran Pradaxa® Increased dabigatran exposure and an increased risk of bleeding Details Sotagliflozin Dabigatran Etexilate Increased dabigatran exposure and an increased risk of bleeding Details Sotagliflozin Digoxin Cardoxin® Increased digoxin exposure Details Sotagliflozin Doxorubicin Adriamycin Increased DOXOrubicin exposure and an increased risk of DOXOrubicin-related adverse reactions Details Sotagliflozin Fentanyl Transdermal Patch Duragesic® Reduced exposure of fentaNYL, reduced efficacy of fentaNYL and/or onset of opioid withdrawal symptoms Details Sotagliflozin Insulin Degludec (Rdna Origin) Injection Ryzodeg® (as a combination product containing Insulin Degludec and Insulin Aspart) An increased risk of hypoglycemia Details Sotagliflozin Insulin Detemir (Rdna Origin) Injection Levemir An increased risk of hypoglycemia Details Sotagliflozin Insulin Glulisine (Rdna Origin) Injection Apidra An increased risk of hypoglycemia Details Sotagliflozin Lefamulin Xenleta Increased lefamulin exposure and an increased risk of lefamulin-related adverse reactions Details Sotagliflozin Levonorgestrel After banger Reduced levonorgestrel exposure and increased risk of breakthrough bleeding and/or contraceptive failure Details Sotagliflozin Levonorgestrel Intrauterine System Kyleena Reduced levonorgestrel exposure and increased risk of breakthrough bleeding and/or contraceptive failure Details Sotagliflozin Lithium Carbonate Lithobid Reduced lithium exposure Details Sotagliflozin Loperamide Diamode Increased loperamide exposure and an increased risk of loperamide-related adverse effects Details Sotagliflozin Lumateperone Caplyta Reduced lumateperone exposure Details Sotagliflozin Nifedipine Adalat® Reduced NIFEdipine exposure Details

Moderate

Sotagliflozin Glimepiride Amaryl An increased risk of hypoglycemia Details Sotagliflozin Glipizide Glucotrol An increased risk of hypoglycemia Details Sotagliflozin Hydrocortisone Ala-Cort Reduced hydrocortisone exposure Details Sotagliflozin Hydrocortisone Injection A-Hydrocort® Reduced hydrocortisone exposure Details Sotagliflozin Nateglinide Starlix® An increased risk of hypoglycemia Details