Indapamide

102 interactions 5 explained in plain English
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Major

Indapamide Acetaminophen And Codeine Capital® & Codeine Explained Reduced diuretic efficacy Details Indapamide Albuterol Oral Inhalation Accuneb® Explained An increased risk of ECG changes or hypokalemia Details Indapamide Buprenorphine Belbuca Explained Reduced efficacy of diuretics Details Indapamide Acarbose Prandase® Explained An increased risk of hyperglycemia and an increased insulin requirement Details Indapamide Arsenic Trioxide Trisenox Increased risk of QT-interval prolongation and torsade de pointes Details Indapamide Arsenic Trioxide Injection Trisenox Increased risk of QT-interval prolongation and torsade de pointes Details Indapamide Aspirin Acuprin® Reduced diuretic effectiveness and possible nephrotoxicity Details Indapamide Aspirin Rectal Aspirin Reduced diuretic effectiveness and possible nephrotoxicity Details Indapamide Alogliptin Nesina An increased risk of hyperglycemia and an increased insulin requirement Details Indapamide Bromfenac Ophthalmic Bromday® Reduced diuretic effectiveness and possible nephrotoxicity Details Indapamide Canagliflozin Invokana An increased risk of hyperglycemia and an increased insulin requirement Details Indapamide Cefepime Injection Maxipime® An increased risk of nephrotoxicity Details Indapamide Dapagliflozin Farxiga An increased risk of hyperglycemia and an increased insulin requirement Details Indapamide Diclofenac Ophthalmic Voltaren® Eye Drops Reduced diuretic effectiveness and possible nephrotoxicity Details Indapamide Diclofenac Topical (Actinic Keratosis) Pennsaid Reduced diuretic effectiveness and possible nephrotoxicity Details Indapamide Diclofenac Topical (Arthritis Pain) Pennsaid® Reduced diuretic effectiveness and possible nephrotoxicity Details Indapamide Diclofenac Transdermal Patch Flector Reduced diuretic effectiveness and possible nephrotoxicity Details Indapamide Digoxin Cardoxin® Increased risk of digitalis toxicity (nausea, vomiting, arrhythmias) Details Indapamide Dulaglutide Injection Trulicity An increased risk of hyperglycemia and an increased insulin requirement Details Indapamide Empagliflozin Glyxambi® (as a combination product containing Empagliflozin and Linagliptin) An increased risk of hyperglycemia and an increased insulin requirement Details Indapamide Etodolac Lodine Reduced diuretic effectiveness and possible nephrotoxicity Details Indapamide Exenatide Injection Bydureon An increased risk of hyperglycemia and an increased insulin requirement Details Indapamide Fenoprofen Fenopron Reduced diuretic effectiveness and possible nephrotoxicity Details Indapamide Fentanyl Transdermal Patch Duragesic® Reduced diuretic efficacy Details Indapamide Flurbiprofen Ansaid Reduced diuretic effectiveness and possible nephrotoxicity Details Indapamide Flurbiprofen Ophthalmic Ocufen Reduced diuretic effectiveness and possible nephrotoxicity Details Indapamide Glimepiride Amaryl An increased risk of hyperglycemia and an increased insulin requirement Details Indapamide Glipizide Glucotrol An increased risk of hyperglycemia and an increased insulin requirement Details Indapamide Hydromorphone Injection Dilaudid Reduced efficacy of diuretics Details Indapamide Hydromorphone Rectal available generically Reduced efficacy of diuretics Details Indapamide Ibuprofen Addaprin Reduced diuretic effectiveness and possible nephrotoxicity Details Indapamide Insulin Degludec (Rdna Origin) Injection Ryzodeg® (as a combination product containing Insulin Degludec and Insulin Aspart) An increased risk of hyperglycemia and an increased insulin requirement Details Indapamide Insulin Detemir (Rdna Origin) Injection Levemir An increased risk of hyperglycemia and an increased insulin requirement Details Indapamide Insulin Glulisine (Rdna Origin) Injection Apidra An increased risk of hyperglycemia and an increased insulin requirement Details Indapamide Ketoprofen Actron® Reduced diuretic effectiveness and possible nephrotoxicity Details Indapamide Ketorolac Acular Reduced diuretic effectiveness and possible nephrotoxicity Details Indapamide Ketorolac Injection Acular Reduced diuretic effectiveness and possible nephrotoxicity Details Indapamide Ketorolac Nasal Spray Sprix Reduced diuretic effectiveness and possible nephrotoxicity Details Indapamide Ketorolac Ophthalmic Acular Reduced diuretic effectiveness and possible nephrotoxicity Details Indapamide Linagliptin Tradjenta An increased risk of hyperglycemia and an increased insulin requirement Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.