Pramlintide

59 interactions 3 explained in plain English

Also sold as: Symlin

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Miglitol Ofloxacin Otic Linagliptin Canagliflozin Octreotide Moxifloxacin

34 Major 25 Moderate

All (59) Major (34) Moderate (25)

Major

Pramlintide Acarbose Prandase® Explained An increased risk of hypoglycemia Details Pramlintide Abiraterone Abirtega An increased risk of severe hypoglycemia Details Pramlintide Alogliptin Nesina An increased risk of hypoglycemia Details Pramlintide Canagliflozin Invokana An increased risk of hypoglycemia Details Pramlintide Chloroquine Aralen® Hypoglycemia Details Pramlintide Dapagliflozin Farxiga An increased risk of hypoglycemia Details Pramlintide Delafloxacin Baxdela Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Pramlintide Delafloxacin Injection Baxdela Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Pramlintide Empagliflozin Glyxambi® (as a combination product containing Empagliflozin and Linagliptin) An increased risk of hypoglycemia Details Pramlintide Ertugliflozin Steglatro An increased risk of hypoglycemia Details Pramlintide Furosemide Injection Disal An increased risk of hyperglycemia and an increased insulin requirement Details Pramlintide Gatifloxacin Ophthalmic Zymar® Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Pramlintide Gemifloxacin Factive Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Pramlintide Glimepiride Amaryl An increased risk of hypoglycemia Details Pramlintide Glipizide Glucotrol An increased risk of hypoglycemia Details Pramlintide Hydroxychloroquine Plaquenil Enhanced hypoglycemic effect of antidiabetics and an increased risk of hypoglycemia Details Pramlintide Insulin Degludec (Rdna Origin) Injection Ryzodeg® (as a combination product containing Insulin Degludec and Insulin Aspart) An increased risk of hypoglycemia Details Pramlintide Insulin Detemir (Rdna Origin) Injection Levemir An increased risk of hypoglycemia Details Pramlintide Insulin Glulisine (Rdna Origin) Injection Apidra An increased risk of hypoglycemia Details Pramlintide Lanreotide Injection Somatuline An increased risk of hypoglycemia and impaired glucose regulation Details Pramlintide Levofloxacin Levaquin Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Pramlintide Levofloxacin Injection Levaquin Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Pramlintide Linagliptin Tradjenta An increased risk of hypoglycemia Details Pramlintide Metformin Fortamet® An increased risk of hypoglycemia Details Pramlintide Miglitol Glyset® An increased risk of hypoglycemia Details Pramlintide Moxifloxacin Avelox Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Pramlintide Moxifloxacin Injection Avelox Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Pramlintide Moxifloxacin Ophthalmic Moxeza® Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Pramlintide Nateglinide Starlix® An increased risk of hypoglycemia Details Pramlintide Octreotide Bynfezia An increased risk of hypoglycemia and impaired glucose regulation Details Pramlintide Octreotide Injection Bynfezia An increased risk of hypoglycemia and impaired glucose regulation Details Pramlintide Ofloxacin Floxin® Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Pramlintide Ofloxacin Ophthalmic Ocuflox Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Pramlintide Ofloxacin Otic Floxin® Otic Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details

Moderate

Pramlintide Lisinopril Prinivil Explained An increased risk of hypoglycemia Details Pramlintide Aspirin Acuprin® Increased risk of hypoglycemia Details Pramlintide Aspirin Rectal Aspirin Increased risk of hypoglycemia Details Pramlintide Atenolol Tenormin Explained Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Pramlintide Acebutolol Sectral® Hypoglycemia or hyperglycemia; decreased symptoms of hypoglycemia Details Pramlintide Benazepril Lotensin An increased risk of hypoglycemia Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.