Tronadora - Symlin (Pramlintide) Interaction

Interaction Details

Pramlintide is classified as belonging to the following category: Antidiabetes Drugs

Theoretically, concomitant use of tronadora and antidiabetes drugs might increase the risk of hypoglycemia. Clinical research suggests that a combination of tronadora and Guazuma ulmifolia reduce levels of fasting glucose in patients with type 2 diabetes, including those already taking antidiabetes agents. The effect of tronadora alone is unknown. Animal research is conflicting.

Interaction Rating

Likelihood of Occurrence

Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists

References

• Costantino L, Raimondi L, Pirisino R, et al. Isolation and pharmacological activities of the Tecoma stans alkaloids. Farmaco 2003;58:781-5.
• Meckes-Lozoya M, Ibanez-Camacho R. Hepatic glycogenolysis produced by intraperitoneal administration of total extract of Tecoma stans in rats. Arch Invest Med (Mex) 1985;16:387-9.
• Roman-Ramos R, Flores-Saenz JL, Partida-Hernandez G, et al. Experimental study of the hypoglycemic effect of some antidiabetic plants. Arch Invest Med (Mex) 1991;22:87-93.
• Pascoe-González S, Ramos-Zavala MG, Buenrostro Ahued MA, et al. Administration of herbarium mixture (Guazuma ulmifolia/Tecoma stans) on metabolic profile in type 2 diabetes mellitus patients: A randomized, double-blind, placebo-controlled trial. J Med Foo
• Gupta A, Behl T, Sehgal A, et al. Elucidating the neuroprotective effect of Tecoma stans leaf extract in STZ-induced diabetic neuropathy. Evid Based Complement Alternat Med 2022;2022:3833392.
• Morales-Ferra DL, Zavala-Sánchez MÁ, Jiménez-Ferrer E, González-Cortazar M, Zamilpa A. Effect of Tecoma stans (L.) Juss. ex Kunth in a murine model of metabolic syndrome. Plants (Basel) 2022;11(14):1794.

Pramlintide Overview

• Pramlintide is used with mealtime insulin to control blood sugar levels in people who have diabetes. Pramlintide is only used to treat patients whose blood sugar could not be controlled by insulin or insulin and an oral medication for diabetes. Pramlintide is in a class of medications called antihyperglycemics. It works by slowing the movement of food through the stomach. This prevents blood sugar from rising too high after a meal, and may decrease appetite and cause weight loss.

• Over time, people who have diabetes and high blood sugar can develop serious or life-threatening complications, including heart disease, stroke, kidney problems, nerve damage, and eye problems. Using medication(s), making lifestyle changes (e.g., diet, exercise, quitting smoking), and regularly checking your blood sugar may help to manage your diabetes and improve your health. This therapy may also decrease your chances of having a heart attack, stroke, or other diabetes-related complications such as kidney failure, nerve damage (numb, cold legs or feet; decreased sexual ability in men and women), eye problems, including changes or loss of vision, or gum disease. Your doctor and other healthcare providers will talk to you about the best way to manage your diabetes.

Tronadora - More Interactions

Tronadora interacts with 84 drugs

Interaction Rating Key

These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.