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Tronadora Drug Interactions, Uses, Effectiveness, Safety & More

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Tronadora Drug Interactions: The Bottom Line

From the HelloPharmacist Editorial Team · Updated July 2026

Based on the available evidence, the overall risk of a clinically significant Tronadora drug interaction appears low for most people, though anyone taking medication for diabetes should pay closer attention. None of the listed interactions are rated major, and every one of them traces back to a single concern: a possible effect on blood sugar.

Interactions deserving the most attention

The interactions that matter here all involve diabetes medications. In theory, tronadora could add to their blood-sugar-lowering effect and raise the chance of hypoglycemia, or low blood sugar. The human research so far tested tronadora combined with another plant, not tronadora on its own, and animal studies point in different directions. So this is a reasonable caution for people on diabetes treatment, not a proven effect.

What the rest of the list means

Although many medications appear on the list, they are essentially the same interaction repeated across every diabetes drug rather than dozens of separate problems. The concern remains largely theoretical, since the effect of tronadora by itself has not been clearly shown in people. For medications outside diabetes care, no interactions have been identified.

Check your medications against Tronadora

Based on HelloPharmacist’s Tronadora interaction data and reviewed under our editorial standards.

Interaction report

Drugs that interact with Tronadora

86 medications have a known interaction with Tronadora, graded by severity. Select any drug for the full evidence-based detail.

2,830 drugs
AcarboseGlucobay, Prandase, Precose› AcetohexamideDymelor› AlbiglutideTanzeum› AlogliptinNesina› Alogliptin, MetforminKazano› Alogliptin, PioglitazoneOseni› Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) InhibitorGlyxambi› CanagliflozinInvokana› Canagliflozin, MetforminInvokamet› Canagliflozin, Metformin HydrochlorideInvokamet XR› ChlorpropamideChlorpropam, Diabinese› DapagliflozinFarxiga› Dapagliflozin Propanediol, MetforminXigduo XR› Dapagliflozin Propanediol, Saxagliptin HydrochlorideQtern› Dapagliflozin, Metformin Hydrochloride, Saxagliptin HydrochlorideQternmet XR› Dasiglucagon HydrochlorideZegalogue› DulaglutideTrulicity› EmpagliflozinJardiance› Empagliflozin, Linagliptin, Metformin HydrochlorideTrijardy XR› Empagliflozin, MetforminSynjardy› Empagliflozin, Metformin HydrochlorideSynjardy XR› ErtugliflozinSteglatro› Ertugliflozin, Metformin HydrochlorideSegluromet› ExenatideBydureon, Byetta› Exenatide SyntheticBydureon BCISE› GliclazideDiamicron› GlimepirideAmaryl› GlipizideGlucotrol, Glucotrol XL› Glipizide, MetforminMetaglip› GlucagonBaqsimi, Glucagon›
Read The List Like a Pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each drug listed above links to the full report for that exact Tronadora combination — clinical detail, likelihood, evidence level, and citations.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
The big picture

The kinds of drugs Tronadora affects

Every type of medication (drug category) Tronadora is known to interact with. Open any category for the detail — or search your exact drug in the checker above.

All 1 drug category Tronadora interacts with
Antidiabetes Drugs
Antidiabetes Drugs

Theoretically, concomitant use of tronadora and antidiabetes drugs might increase the risk of hypoglycemia. Clinical research suggests that a combination of tronadora and Guazuma ulmifolia reduce levels of fasting glucose in patients with type 2 diabetes, including those already taking antidiabetes agents. The effect of tronadora alone is unknown. Animal research is conflicting.

Likelihood Possible Evidence B
Monograph

Tronadora: Uses, Safety & Side Effects

The bottom line

Tronadora (Tecoma stans) is a flowering shrub used in Mexican and Latin American folk medicine, most often as a tea for diabetes and digestive complaints. Human evidence is very limited, so it should not replace proven treatments. Because it may affect blood sugar and its safety is not well studied, talk to your pharmacist or doctor before using it—and avoid it during pregnancy and breastfeeding.

Scientific name
Tecoma stans
Family
Bignoniaceae
Part used
Leaves, flowers, and sometimes roots and bark
Common forms
Tea (infusion), dried herb, capsules, liquid extracts
People commonly use it for
  • Blood sugar control / diabetes
  • Digestive complaints
  • Mild fever
  • Yeast or fungal concerns
  • Traditional 'tonic' use

Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.

Safety at a glance
OverallUse caution

Limited human safety data; may affect blood sugar, so use with care and medical guidance.

PregnancyInsufficient reliable information

Insufficient reliable information available; avoid using.

Read the full pregnancy detail
BreastfeedingInsufficient reliable information

Insufficient reliable information available; avoid using.

Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

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Overview

Tronadora is a common name for Tecoma stans, a flowering shrub or small tree also known as yellow trumpetbush or yellow bells. It grows in Mexico, Central and South America, and other warm regions, and is often grown as an ornamental plant for its bright yellow, trumpet-shaped flowers.

In traditional Mexican and Latin American herbal medicine, the leaves and flowers are most often prepared as a tea. People have used it for generations as a home remedy, and you may also find it sold as a dried herb, in capsules, or as a liquid extract.

How it works

Tecoma stans contains natural compounds such as alkaloids (including ones reported as tecomine and tecostanine), flavonoids, and other plant chemicals. In laboratory and animal studies, some of these compounds have shown effects that could lower blood sugar or act as antioxidants.

It's important to understand that these are proposed mechanisms based mainly on lab and animal research. We do not have solid proof of how—or whether—the herb works the same way in the human body.

Effectiveness

Does Tronadora work?

Evidence overview · 1 use evaluated
1 Insufficient evidence
How to read these evidence grades

Natural Medicines’ 7-point scale. We show each rating’s label word-for-word.

1EffectiveStrong, consistent evidence it works.
2Likely EffectiveGood evidence, though not yet conclusive.
3Possibly EffectiveSome evidence suggests a benefit.
4Possibly IneffectiveSome evidence it may not help.
5Likely IneffectiveFairly strong evidence it doesn’t help.
6IneffectiveStrong evidence it doesn’t work.
7Insufficient Reliable Evidence to RateToo little research to say either way.

For Tronadora, current evidence isn’t strong enough to rate any specific use. The conditions it has been studied for are listed below.

Also studied for 1 condition — evidence insufficient to rate
Insufficient Reliable Evidence To Rate Diabetes
Rating & evidence shown verbatim from Natural Medicines

A small clinical trial in patients with type 2 diabetes shows that taking a combination of tronadora 100 mg and Guazuma ulmifolia 300 mg each before meals for 90 days modestly improves levels of fasting glucose and glycated hemoglobin when compared with taking placebo. Most patients were taking oral antidiabetic agents and or insulin. It is unclear if any benefits are due to tronadora, Guazuma ulmifolia, or the combination.

Sources Ref 110886

Source & disclaimer. Effectiveness ratings and evidence summaries are provided by Natural Medicines (Therapeutic Research Center) and shown as licensed. Where Natural Medicines hasn’t rated a use, HelloPharmacist’s pharmacists may add their own reviewed rating and evidence (each such entry is labeled). This is educational information, not medical advice — talk with your pharmacist or doctor before starting, stopping, or changing a supplement.

Safety & precautions

The safety of Tronadora has not been well studied in people. Because it may lower blood sugar, people with diabetes should be especially careful, as blood sugar could drop too low, particularly if they also take blood-sugar medicines.

People with liver or kidney problems, and anyone scheduled for surgery, should talk to a healthcare provider before using it. Pregnant and breastfeeding women should avoid Tronadora because there is not enough information to know it is safe. It is also not recommended for children.

Always tell your pharmacist or doctor about any herbal products you take.

Side effects

Because Tronadora has not been studied carefully in humans, its full side-effect profile is unknown. Possible effects could include stomach upset, nausea, or low blood sugar (which can cause shakiness, sweating, dizziness, or confusion).

As with any plant product, allergic reactions are possible. Stop using it and seek medical care if you notice rash, swelling, trouble breathing, or other signs of a serious reaction.

Tronadora: Reported Adverse Effects

Documented safety reports on Tronadora from the evidence-graded Natural Medicines (TRC Healthcare) database, shown word-for-word from the licensed record.

There is currently a limited amount of information available about adverse effects of tronadora. Topically, tronadora might cause allergic dermatitis.

  1. Lakshmi C. Fingertip eczema to pooja flowers: Allergic contact dermatitis to Tabernaemontana divaricata and Tecoma stans. Indian J Dermatol Venereol Leprol. 2015;81(5):514-6.
Reports by condition
Dermatitis Dermatologic

Topically, tronadora might cause allergic dermatitis. In one case report, an Indian woman that regularly plucked tronadora flowers as part of her morning pooja ritual developed allergic dermatitis.

  1. Lakshmi C. Fingertip eczema to pooja flowers: Allergic contact dermatitis to Tabernaemontana divaricata and Tecoma stans. Indian J Dermatol Venereol Leprol. 2015;81(5):514-6.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

Adverse-effects data: Natural Medicines, Therapeutic Research Center

Dosing

There is no established, standardized dose for Tronadora. Traditional use is often as a tea made from the dried leaves or flowers, but the amount of active compounds can vary a lot between products and batches.

If you choose to use it, follow the directions on the product label and start low. Because doses are not well defined and the herb may affect blood sugar, it is best to check with your pharmacist or doctor first—especially if you have diabetes or take any medicines.

Pregnancy & Breastfeeding

Tronadora & Pregnancy

Insufficient reliable information

Insufficient reliable information available; avoid using.

Tronadora & Breastfeeding

Insufficient reliable information

Insufficient reliable information available; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

© 2026 Therapeutic Research Center

Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center

References & further reading

The 7 references that drive our Tronadora monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Costantino L, Raimondi L, Pirisino R, et al. Isolation and pharmacological activities of the Tecoma stans alkaloids. Farmaco 2003;58:781-5. PubMed
  2. Meckes-Lozoya M, Ibanez-Camacho R. Hepatic glycogenolysis produced by intraperitoneal administration of total extract of Tecoma stans in rats. Arch Invest Med (Mex) 1985;16:387-9.
  3. Roman-Ramos R, Flores-Saenz JL, Partida-Hernandez G, et al. Experimental study of the hypoglycemic effect of some antidiabetic plants. Arch Invest Med (Mex) 1991;22:87-93.
  4. Lakshmi C. Fingertip eczema to pooja flowers: Allergic contact dermatitis to Tabernaemontana divaricata and Tecoma stans. Indian J Dermatol Venereol Leprol. 2015;81(5):514-6. PubMed
  5. Pascoe-González S, Ramos-Zavala MG, Buenrostro Ahued MA, et al. Administration of herbarium mixture (Guazuma ulmifolia/Tecoma stans) on metabolic profile in type 2 diabetes mellitus patients: A randomized, double-blind, placebo-controlled trial. J Med Foo
  6. Gupta A, Behl T, Sehgal A, et al. Elucidating the neuroprotective effect of Tecoma stans leaf extract in STZ-induced diabetic neuropathy. Evid Based Complement Alternat Med 2022;2022:3833392. PubMed
  7. Morales-Ferra DL, Zavala-Sánchez MÁ, Jiménez-Ferrer E, González-Cortazar M, Zamilpa A. Effect of Tecoma stans (L.) Juss. ex Kunth in a murine model of metabolic syndrome. Plants (Basel) 2022;11(14):1794. PubMed
Keep reading

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Pharmacist Counseling Corner

Tronadora: Common Questions

What is Tronadora used for, and does it work?
People use Tronadora for a range of reasons, but according to the Natural Medicines database the current clinical evidence is insufficient to confirm it works for the specific conditions it has been studied for. See the graded list on this page, and talk to your pharmacist or doctor before relying on it for any condition.
Does Tronadora interact with prescription medications?
Yes. We list 86 medications with a known interaction with Tronadora. Use the checker above to see how Tronadora interacts with a specific drug.
How are Tronadora interactions rated?
Each interaction is graded major, moderate, or minor based on how clinically significant it is and the strength of the evidence behind it. Major interactions are the most serious and are best avoided, or used only under close professional supervision.
Is it safe to take Tronadora with my medications?
It depends on the specific medication. Some combinations are fine, while others call for monitoring, timing changes, or should be avoided. Check your exact drug above and confirm with your pharmacist or doctor before starting, stopping, or changing anything.
Where does this Tronadora interaction information come from?
Our interaction data is built on the Natural Medicines database — an evidence-graded reference for vitamins, herbs, and supplements — and is reviewed by licensed HelloPharmacist pharmacists, who may add clinical context.
What is Tronadora used for?
It is used in traditional Latin American medicine mainly for diabetes and high blood sugar, as well as for digestive complaints and mild fever. However, there is little solid human evidence that it works for these uses.
Is Tronadora safe to take?
Its safety has not been well studied in people. It may lower blood sugar and could cause stomach upset or allergic reactions, so it's best to talk with a pharmacist or doctor before using it.
Can I use Tronadora if I am pregnant or breastfeeding?
No. There is not enough reliable safety information, so it is best to avoid Tronadora during pregnancy and while breastfeeding.
Can Tronadora replace my diabetes medication?
No. There is no good proof that it controls blood sugar safely in people, and it should never replace your prescribed diabetes treatment. Talk to your doctor before adding any herb.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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