Dichlorphenamide

Name: Dichlorphenamide Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

8 interactions

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Aspirin Aspirin Rectal Acyclovir Acyclovir Injection Acyclovir Ophthalmic Acyclovir Topical

2 Contraindicated 6 Major

All (8) Contraindicated (2) Major (6)

Contraindicated

Dichlorphenamide Aspirin Acuprin® Increased salicylate exposure , increased dichlorphenamide exposure and its toxicity Details Dichlorphenamide Aspirin Rectal Aspirin Increased salicylate exposure , increased dichlorphenamide exposure and its toxicity Details

Major

Dichlorphenamide Acyclovir Avaclyr Increased OAT1 substrate exposure Details Dichlorphenamide Acyclovir Injection Avaclyr Increased OAT1 substrate exposure Details Dichlorphenamide Acyclovir Ophthalmic Avaclyr Increased OAT1 substrate exposure Details Dichlorphenamide Acyclovir Topical Zovirax Increased OAT1 substrate exposure Details Dichlorphenamide Furosemide Injection Disal Increased OAT1 substrate exposure Details Dichlorphenamide Metformin Fortamet® An increased risk of lactic acidosis and reduced serum bicarbonate Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.