Midazolam Nasal Spray

Contraindicated

Midazolam Nasal Spray Amprenavir An increased risk of midazolam toxicity (excessive sedation, confusion) Details Midazolam Nasal Spray Atazanavir Reyataz Increased midazolam exposure Details Midazolam Nasal Spray Boceprevir Increased midazolam concentrations Details Midazolam Nasal Spray Cobicistat Tybost Increased midazolam plasma concentrations and increased risk for serious adverse effects including, prolonged or increased sedatio... Details Midazolam Nasal Spray Darunavir Increased midazolam exposure and an increased risk of prolonged sedation or respiratory depression Details Midazolam Nasal Spray Delavirdine Rescriptor® Increased midazolam concentrations Details Midazolam Nasal Spray Ensitrelvir Increased CYP3A substrates exposure and an increased risk of CYP3A substrates-related adverse effects Details Midazolam Nasal Spray Flumazenil Increased risk of serious adverse effects in patients who are physically dependent on benzodiazepines, including seizures Details Midazolam Nasal Spray Fosamprenavir Lexiva An increased risk of midazolam toxicity (excessive sedation, confusion, respiratory depression) Details Midazolam Nasal Spray Indinavir Increased midazolam plasma concentrations Details Midazolam Nasal Spray Isocarboxazid Marplan An increased risk of CNS depression Details Midazolam Nasal Spray Itraconazole Sporanox Increased midazolam exposure and an increased risk of midazolam-related adverse effects (respiratory depression) Details Midazolam Nasal Spray Ketoconazole Extina Increased midazolam exposure and potentially increased midazolam toxicity (excessive sedation and prolonged hypnotic effects) Details Midazolam Nasal Spray Levoketoconazole Recorlev Increased CYP3A4 substrate exposure and an increased risk of sensitive CYP3A4 substrate-related adverse reaction Details Midazolam Nasal Spray Lonafarnib Zokinvy Increased midazolam exposure and an increased risk of midazolam-related adverse effects Details Midazolam Nasal Spray Lopinavir Increased midazolam plasma concentrations Details Midazolam Nasal Spray Nelfinavir Viracept Increased midazolam exposure and an increase risk of prolonged sedation or respiratory depression Details Midazolam Nasal Spray Nirmatrelvir An increased risk of extreme sedation and respiratory depression Details Midazolam Nasal Spray Ritonavir Norvir An increased risk of extreme sedation and respiratory depression Details Midazolam Nasal Spray Saquinavir An increased risk of midazolam toxicity (excessive sedation, respiratory depression) Details Midazolam Nasal Spray Telaprevir Increased midazolam concentrations and risk of prolonged sedation or respiratory depression Details Midazolam Nasal Spray Tipranavir Aptivus An increased risk of extreme sedation and respiratory depression Details

Major

Midazolam Nasal Spray Adagrasib Krazati Increased CYP3A4 substrate exposure Details Midazolam Nasal Spray Alfentanil Increased risk of respiratory or CNS depression and hypotension Details Midazolam Nasal Spray Alprazolam Xanax Increased risk of hypoventilation, airway obstruction, desaturation, or apnea Details Midazolam Nasal Spray Amobarbital Amytal Increased risk of hypoventilation, airway obstruction, desaturation, or apnea Details Midazolam Nasal Spray Anileridine Increased risk of hypoventilation, airway obstruction, desaturation, or apnea Details Midazolam Nasal Spray Apalutamide Erleada Reduced CYP3A4 substrate exposure Details Midazolam Nasal Spray Aprobarbital Increased risk of hypoventilation, airway obstruction, desaturation, or apnea Details Midazolam Nasal Spray Aripiprazole Abilify An increased risk of sedation and orthostatic hypotension Details Midazolam Nasal Spray Aripiprazole Lauroxil Aristada An increased risk of sedation and orthostatic hypotension Details Midazolam Nasal Spray Avacopan Tavneos Increased CYP3A4 substrate exposure Details Midazolam Nasal Spray Baclofen Fleqsuvy Increased risk of hypoventilation, airway obstruction, desaturation, or apnea Details Midazolam Nasal Spray Benzhydrocodone Increased risk of respiratory and CNS depression Details Midazolam Nasal Spray Bromazepam Increased risk of respiratory or cardiovascular depression Details Midazolam Nasal Spray Bromopride Potentiation of sedative effects Details Midazolam Nasal Spray Buprenorphine Belbuca An increased risk of CNS depression and respiratory depression Details Midazolam Nasal Spray Buspirone Bucapsol Increased risk of hypoventilation, airway obstruction, desaturation, or apnea Details Midazolam Nasal Spray Butabarbital Increased risk of hypoventilation, airway obstruction, desaturation, or apnea Details Midazolam Nasal Spray Butalbital Increased risk of hypoventilation, airway obstruction, desaturation, or apnea Details