Betaxolol Ophthalmic

161 interactions 395 cited references
Also sold as: Betoptic® Betoptic® S
About Betaxolol Ophthalmic

Ophthalmic betaxolol is used to treat glaucoma, a condition in which increased pressure in the eye can lead to gradual loss of vision. Betaxolol is in a class of medications called beta blockers. It works by decreasing the pressure in the eye. Read the full Betaxolol Ophthalmic drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Major

Betaxolol Ophthalmic Albuterol ProAir Reduced efficacy of albuterol Details Betaxolol Ophthalmic Ceritinib Zykadia Increased risk of bradycardia Details Betaxolol Ophthalmic Clonidine Duraclon An increased risk of worsen sinus node dysfunction and atrioventricular node conduction, an increased risk of bradycardia and AV b... Details Betaxolol Ophthalmic Crizotinib Xalkori An increased risk of bradycardia Details Betaxolol Ophthalmic Darunavir Increased beta blocker exposure and an increased risk of beta blocker-related adverse effects Details Betaxolol Ophthalmic Diltiazem Cardizem An increased risk of hypotension, bradycardia and slow AV conduction Details Betaxolol Ophthalmic Disopyramide Norpace Severe bradycardia, asystole and heart failure Details Betaxolol Ophthalmic Dronedarone Multaq Increased exposure to some beta blockers and increased incidence of bradycardia Details Betaxolol Ophthalmic Epinephrine Antagonized cardio stimulating and bronchodilation effects of EPINEPHrine, an increased risk of severe hypertension and an increas... Details Betaxolol Ophthalmic Fenoldopam Exaggeration of hypotensive response Details Betaxolol Ophthalmic Fingolimod Gilenya Slowing of the heart rate or atrioventricular conduction, which may result in severe bradycardia or heart block Details Betaxolol Ophthalmic Formoterol Perforomist Reduced efficacy of formoterol or reduced efficacy of beta-adrenergic blocker Details Betaxolol Ophthalmic Indacaterol Decreased efficacy of indacaterol Details Betaxolol Ophthalmic Insulin Afrezza Increased or reduced blood glucose lowering effect of insulin and reduced symptoms of hypoglycemia Details Betaxolol Ophthalmic Insulin Icodec-Abae Awiqli An increased risk of hypoglycemia, which may sometimes be followed by hyperglycemia and an increased risk of blunted recognition o... Details Betaxolol Ophthalmic Iohexol Lower threshold for contrast reactions, increased risk of more severe contrast reaction, reduced efficacy when treating hypersensi... Details Betaxolol Ophthalmic Lacosamide Motpoly An increased risk of AV block, bradycardia, and ventricular tachyarrhythmia Details Betaxolol Ophthalmic Landiolol An increased risk of myocardial contractility depression and increase the risk of bradycardia or heart block Details Betaxolol Ophthalmic Levalbuterol Xopenex Reduced efficacy of levalbuterol Details Betaxolol Ophthalmic Melatonin An increased risk of suppression of endogenous melatonin levels Details Betaxolol Ophthalmic Methylergonovine Methergine An increased risk of enhanced vasoconstrictive Details Betaxolol Ophthalmic Olodaterol Striverdi Reduced olodaterol exposure and reduced beta-adrenergic blockers exposure Details Betaxolol Ophthalmic Phenelzine Nardil An increased risk of exaggerated hypotensive effect and an increased risk of bradycardia Details Betaxolol Ophthalmic Ponesimod Ponvory An increased risk of severe bradycardia and heart block Details Betaxolol Ophthalmic Rivastigmine Exelon Additive bradycardic effects Details Betaxolol Ophthalmic Salmeterol Serevent Reduced efficacy of salmeterol Details Betaxolol Ophthalmic Siponimod Mayzent An increased risk of severe bradycardia and heart block Details Betaxolol Ophthalmic Terbutaline Brethine® Reduced efficacy of terbutaline Details Betaxolol Ophthalmic Verapamil Calan An increased risk of hypotension, bradycardia and slow AV conduction Details Betaxolol Ophthalmic Vilanterol Decreased efficacy of vilanterol Details

Check another drug

Still have questions about this combination?

Every question gets a real answer from a licensed pharmacist — free, and usually within a day.

Ask the pharmacist
Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.