Aprepitant

Major

Aprepitant Acetaminophen And Codeine Capital® & Codeine Explained Increased codeine and morphine exposure Details Aprepitant Buprenorphine Belbuca Explained Increased buprenorphine exposure and an increased risk of buprenorphine-related adverse events Details Aprepitant Colchicine Colcrys Explained Increased colchicine exposure and an increased risk of fatal toxicity Details Aprepitant Acalabrutinib Calquence Increased acalabrutinib exposure and increased risk of toxicity Details Aprepitant Atogepant Qulipta Reduced atogepant exposure Details Aprepitant Avapritinib Ayvakit Increased avapritinib exposure and an increased risk of the incidence and severity of adverse reactions Details Aprepitant Cariprazine Vraylar Explained Increased cariprazine and its major active metabolite (didesmethylcariprazine (DDCAR)) exposure Details Aprepitant Amlodipine Amvaz® Increased amLODIPine exposure, an increased risk of hypotension and edema and reduced amLODIPine exposure Details Aprepitant Bedaquiline Sirturo Increased bedaquiline exposure Details Aprepitant Bosutinib Bosulif Increased bosutinib exposure Details Aprepitant Brexpiprazole Rexulti Increased brexpiprazole exposure Details Aprepitant Brigatinib Alunbrig Increased brigatinib exposure Details Aprepitant Budesonide Entocort Increased budesonide exposure Details Aprepitant Budesonide Nasal Spray Rhinocort Increased budesonide exposure Details Aprepitant Budesonide Oral Inhalation Pulmicort Increased budesonide exposure Details Aprepitant Cobimetinib Cotellic Increased cobimetinib plasma concentrations Details Aprepitant Cyclosporine Injection Atopica Increased cycloSPORINE exposure Details Aprepitant Cyclosporine Ophthalmic Cequa Increased cycloSPORINE exposure Details Aprepitant Deflazacort Emflaza Increased exposure to active metabolite of deflazacort Details Aprepitant Diazepam Nasal Spray Valtoco Increased exposure to benzodiazepines and an increased risk of benzodiazepine-related adverse reactions Details Aprepitant Diazepam Rectal Diastat Increased exposure to benzodiazepines and an increased risk of benzodiazepine-related adverse reactions Details Aprepitant Dihydroergotamine Injection DHE-45® Injection Increased dihydroergotamine exposure and an increased risk of ergotism (nausea, vomiting, vasospastic ischemia) Details Aprepitant Dihydroergotamine Nasal Spray Migranal Increased dihydroergotamine exposure and an increased risk of ergotism (nausea, vomiting, vasospastic ischemia) Details Aprepitant Docetaxel Beizray Increased chemotherapeutic agent exposure Details Aprepitant Docetaxel Injection Beizray Increased chemotherapeutic agent exposure Details Aprepitant Doxorubicin Adriamycin Increased doxorubicin exposure and an increased risk of doxorubicin-related adverse reactions Details Aprepitant Elacestrant Orserdu Increased elacestrant exposure and an increased risk of elacestrant-related adverse effects Details Aprepitant Encorafenib Braftovi Increased encorafenib exposure, an increased risk of encorafenib-related adverse reactions, reduced sensitive CYP3A4 substrate exp... Details Aprepitant Entrectinib Rozlytrek Increased entrectinib exposure and an increased frequency or severity of adverse reactions Details Aprepitant Estradiol Delestrogen Reduced hormonal contraceptive exposure, reduced efficacy of hormonal contraceptives and an increased risk of breakthrough bleedin... Details Aprepitant Estradiol Topical Divigel Reduced hormonal contraceptive exposure, reduced efficacy of hormonal contraceptives and an increased risk of breakthrough bleedin... Details Aprepitant Estradiol Transdermal Patch Alora® Reduced hormonal contraceptive exposure, reduced efficacy of hormonal contraceptives and an increased risk of breakthrough bleedin... Details Aprepitant Fentanyl Transdermal Patch Duragesic® Increased fentaNYL exposure and an increased risk of prolonged opioid effects Details Aprepitant Finerenone Kerendia Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Aprepitant Ibrutinib Imbruvica Increased ibrutinib exposure Details Aprepitant Ifosfamide Injection Ifex Increased chemotherapeutic agent exposure Details Aprepitant Infigratinib Truseltiq Increased infigratinib plasma concentrations Details Aprepitant Ivabradine Corlanor Increased exposure of ivabradine Details Aprepitant Ketoconazole Topical Extina® Foam Increased aprepitant or fosaprepitant (prodrug of aprepitant) exposure Details Aprepitant Lefamulin Xenleta Increased lefamulin exposure, an increased risk of lefamulin-related adverse reactions, an increased strong and moderate CYP3A4 in... Details