Dronabinol

23 interactions 92 cited references
Also sold as: Marinol Marinol® Syndros Syndros®
About Dronabinol

Dronabinol is used to treat nausea and vomiting caused by chemotherapy in people who have already taken other medications to treat this type of nausea and vomiting without good results. Dronabinol is also used to treat loss of appetite and weight loss in people who have acquired immunodeficiency syndrome (AIDS). Dronab… Read the full Dronabinol drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Major

Dronabinol Capecitabine Xeloda Increased exposure of CYP2C9 substrates and an increased risk of CYP2C9 substrates-related adverse effects Details Dronabinol Apalutamide Erleada Reduced CYP2C9 substrates exposure Details Dronabinol Carbamazepine Carbatrol Reduced CYP2C9 substrate exposure and reduced efficacy of CYP2C9 substrate Details Dronabinol Clomipramine Anafranil Increased clomiPRAMINE exposure Details Dronabinol Deutivacaftor Increased CYP2C9 substrate exposure Details Dronabinol Dextroamphetamine Dexedrine Increased dextroamphetamine or lisdexamfetamine (prodrug of dextroamphetamine) exposure and an increased risk of serotonin syndrom... Details Dronabinol Doxifluridine Increased exposure of CYP2C9 substrates and an increased risk of CYP2C9 substrates-related adverse effects Details Dronabinol Fluorouracil Adrucil Increased exposure of CYP2C9 substrates and an increased risk of CYP2C9 substrates-related adverse effects Details Dronabinol Haloperidol Increased haloperidol exposure and an increased risk of haloperidol-related adverse events, including QTc interval prolongation Details Dronabinol Itraconazole Sporanox Increased cannabinoid exposure and an increased risk of cannabinoid-related adverse effects Details Dronabinol Lisdexamfetamine Arynta Increased dextroamphetamine or lisdexamfetamine (prodrug of dextroamphetamine) exposure and an increased risk of serotonin syndrom... Details Dronabinol Tegafur Increased exposure of CYP2C9 substrates and an increased risk of CYP2C9 substrates-related adverse effects Details Dronabinol Tramadol ConZip Increased traMADol exposure and reduced exposure of the active metabolite Details Dronabinol Voriconazole Vfend Increased CYP2C9 substrates exposure and an increased efficacy of CYP2C9 substrates-related adverse effects Details Dronabinol Fluorouracil Injection Adrucil Increased exposure of CYP2C9 substrates and an increased risk of CYP2C9 substrates-related adverse effects Details Dronabinol Fluorouracil Topical Carac Increased exposure of CYP2C9 substrates and an increased risk of CYP2C9 substrates-related adverse effects Details

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