Sofosbuvir
16 interactions 2 explained in plain EnglishSofosbuvir is used along with ribavirin (Copegus, Rebetol, Ribasphere, others) and sometimes another medication (peginterferon alfa [Pegasys]) to treat certain types of chronic hepatitis C (an ongoing viral infection that damages the liver) in adults. Sofosbuvir is also used along with ribavirin to treat certain types… Read the full Sofosbuvir drug information page →
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Contraindicated
Sofosbuvir Colchicine Colcrys Explained Increased colchicine exposure and an increased risk of colchicine toxicity DetailsMajor
Sofosbuvir Relugolix Orgovyx Explained Increased relugolix exposure Details Sofosbuvir Asciminib Scemblix Increased BCRP substrate exposure and an increased risk of BCRP substrate-related adverse effects Details Sofosbuvir Atorvastatin Atorvaliq An increased risk of myopathy and rhabdomyolysis Details Sofosbuvir Capmatinib Tabrecta Increased P-gp substrate exposure and an increased risk of increased adverse reactions Details Sofosbuvir Cyclosporine Injection Atopica Increased cycloSPORINE exposure Details Sofosbuvir Cyclosporine Ophthalmic Cequa Increased cycloSPORINE exposure Details Sofosbuvir Dabigatran Pradaxa® Increased dabigatran exposure and an increased risk of bleeding Details Sofosbuvir Dabigatran Etexilate Increased dabigatran exposure and an increased risk of bleeding Details Sofosbuvir Doxorubicin Adriamycin Increased DOXOrubicin exposure and an increased risk of DOXOrubicin-related adverse reactions Details Sofosbuvir Lefamulin Xenleta Increased lefamulin exposure and an increased risk of lefamulin-related adverse reactions Details Sofosbuvir Lenacapavir Injection Sunlenca Increased P-gp substrate exposure and an increased risk of P-gp substrate-related adverse reactions Details Sofosbuvir Lenacapavir Oral Sunlenca Increased P-gp substrate exposure and an increased risk of P-gp substrate-related adverse reactions Details Sofosbuvir Leniolisib Joenja Increased BCRP substrate exposure Details Sofosbuvir Morphine Injection Astramorph® PF Increased morphine exposure and an increased risk of morphine-related adverse effects (hypotension, respiratory depression, profou... DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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