Clotrimazole Lozenge

35 interactions 186 cited references
Also sold as: Mycelex®
About Clotrimazole Lozenge

Clotrimazole lozenges are used to treat yeast infections of the mouth in adults and children 3 years of age and older. It can also be used to prevent yeast infections of the mouth in people at risk of these infections who are receiving certain treatments. Clotrimazole is in a class of antifungal medications called imid… Read the full Clotrimazole Lozenge drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Major

Clotrimazole Lozenge Alfentanil Increased ALfentanil exposure and an increased risk of respiratory depression Details Clotrimazole Lozenge Bedaquiline Sirturo Increased bedaquiline exposure Details Clotrimazole Lozenge Colchicine Colcrys Increased colchicine exposure and an increased risk of colchicine-related toxicity Details Clotrimazole Lozenge Dihydroergotamine Brekiya Increased ergot derivatives exposure and an increased risk of ergotism (nausea, vomiting, vasospastic ischemia) Details Clotrimazole Lozenge Doxorubicin Adriamycin Increased doxorubicin exposure and an increased risk of doxorubicin-related adverse reactions Details Clotrimazole Lozenge Doxorubicin Hydrochloride Liposome Increased doxorubicin exposure and an increased risk of doxorubicin-related adverse reactions Details Clotrimazole Lozenge Ergoloid Mesylates Alkergot® Increased ergot derivatives exposure and an increased risk of ergotism (nausea, vomiting, vasospastic ischemia) Details Clotrimazole Lozenge Ergonovine Increased ergot derivatives exposure and an increased risk of ergotism (nausea, vomiting, vasospastic ischemia) Details Clotrimazole Lozenge Ergotamine Ergomar Increased ergot derivatives exposure and an increased risk of ergotism (nausea, vomiting, vasospastic ischemia) Details Clotrimazole Lozenge Finerenone Kerendia Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Clotrimazole Lozenge Haloperidol Increased haloperidol exposure and an increased risk of haloperidol-related adverse events, including QTc interval prolongation Details Clotrimazole Lozenge Lemborexant Dayvigo Increased lemborexant exposure and an increased risk of lemborexant-related adverse reactions. Details Clotrimazole Lozenge Lisuride Increased ergot derivatives exposure and an increased risk of ergotism (nausea, vomiting, vasospastic ischemia) Details Clotrimazole Lozenge Lomitapide Increased lomitapide exposure Details Clotrimazole Lozenge Loperamide Diamode Increased loperamide exposure and an increased risk of loperamide-related adverse reactions Details Clotrimazole Lozenge Meperidine Demerol Increased meperidine exposure and risk of increased or prolonged opioid effects Details Clotrimazole Lozenge Metergoline Increased ergot derivatives exposure and an increased risk of ergotism (nausea, vomiting, vasospastic ischemia) Details Clotrimazole Lozenge Methylergonovine Methergine Increased ergot derivatives exposure and an increased risk of ergotism (nausea, vomiting, vasospastic ischemia) Details Clotrimazole Lozenge Methysergide Increased ergot derivatives exposure and an increased risk of ergotism (nausea, vomiting, vasospastic ischemia) Details Clotrimazole Lozenge Mifepristone Korlym Increased miFEPRIStone exposure Details Clotrimazole Lozenge Nicergoline Increased ergot derivatives exposure and an increased risk of ergotism (nausea, vomiting, vasospastic ischemia) Details Clotrimazole Lozenge Nifedipine Adalat® Increased NIFEdipine exposure Details Clotrimazole Lozenge Paclitaxel Abraxane Increased PACLitaxel exposure Details Clotrimazole Lozenge Paclitaxel Protein-Bound Increased PACLitaxel exposure Details Clotrimazole Lozenge Pimozide Increased pimozide exposure Details Clotrimazole Lozenge Roflumilast Daliresp Increased roflumilast exposure and an increased risk of roflumilast-related adverse events Details Clotrimazole Lozenge Tacrolimus Astagraf Increased tacrolimus concentration and an increased risk of toxicity Details Clotrimazole Lozenge Tramadol ConZip Increased traMADol exposure and an increased risk of seizures, serotonin syndrome and opioid toxicity Details Clotrimazole Lozenge Voriconazole Vfend Increased voriconazole exposure and an increased risk of voriconazole-related adverse reaction Details

Check another drug

Still have questions about this combination?

Every question gets a real answer from a licensed pharmacist — free, and usually within a day.

Ask the pharmacist
Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.