Streptokinase

21 interactions 1 explained in plain English
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 11, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Defibrotide Injection Lecanemab-Irmb Injection Edoxaban Enoxaparin Injection Heparin Injection Fondaparinux
1 Contraindicated 15 Major 5 Moderate
All (21) Contraindicated (1) Major (15) Moderate (5)

Contraindicated

Streptokinase Defibrotide Injection Defitelio Increased risk of bleeding Details

Major

Streptokinase Apixaban Eliquis Explained An increased risk of bleeding Details Streptokinase Betrixaban Bevyxxa® Increased risk of bleeding Details Streptokinase Caplacizumab-Yhdp Injection Cablivi Increased risk of bleeding Details Streptokinase Dabigatran Pradaxa® An increased risk of bleeding Details Streptokinase Dabigatran Etexilate An increased risk of bleeding Details Streptokinase Dalteparin Injection Fragmin An increased risk of bleeding Details Streptokinase Dipyridamole Permole® An increased risk of bleeding Details Streptokinase Edoxaban Savaysa An increased risk of bleeding Details Streptokinase Enoxaparin Lovenox Increased risk of bleeding Details Streptokinase Enoxaparin Injection Lovenox Increased risk of bleeding Details Streptokinase Fondaparinux Arixtra An increased risk of bleeding Details Streptokinase Fondaparinux Injection Arixtra An increased risk of bleeding Details Streptokinase Heparin An increased risk of bleeding Details Streptokinase Heparin Injection Lipo-Hepin® An increased risk of bleeding Details Streptokinase Lecanemab-Irmb Injection Leqembi An increased risk of amyloid related imaging abnormalities or intracerebral hemorrhage Details

Moderate

Streptokinase Aspirin Acuprin® An increased risk of hemorrhagic complications Details Streptokinase Aspirin Rectal Aspirin An increased risk of hemorrhagic complications Details Streptokinase Capsaicin Arthricare for Women Moisturizing Increased risk of bleeding Details Streptokinase Capsaicin Topical Aspercreme Warming® Increased risk of bleeding Details Streptokinase Capsaicin Transdermal Patch Aspercreme Warming® Patch Increased risk of bleeding Details

Check another drug

Still have questions about this combination?

Every question gets a real answer from a licensed pharmacist — free, and usually within a day.

Ask the pharmacist
Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.