Feverfew

37 interactions
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 11, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Naproxen Ketoprofen Nabumetone Ketorolac Ophthalmic Flurbiprofen Ketorolac
23 Major 14 Moderate
All (37) Major (23) Moderate (14)

Major

Feverfew Aspirin Acuprin® Increased risk of adverse effects from the nonsteroidal antiinflammatory agent (ie, gastrointestinal, renal effects) Details Feverfew Aspirin Rectal Aspirin Increased risk of adverse effects from the nonsteroidal antiinflammatory agent (ie, gastrointestinal, renal effects) Details Feverfew Bromfenac Ophthalmic Bromday® Increased risk of adverse effects from the nonsteroidal antiinflammatory agent (ie, gastrointestinal, renal effects) Details Feverfew Diclofenac Ophthalmic Voltaren® Eye Drops Increased risk of adverse effects from the nonsteroidal antiinflammatory agent (ie, gastrointestinal, renal effects) Details Feverfew Diclofenac Topical (Actinic Keratosis) Pennsaid Increased risk of adverse effects from the nonsteroidal antiinflammatory agent (ie, gastrointestinal, renal effects) Details Feverfew Diclofenac Topical (Arthritis Pain) Pennsaid® Increased risk of adverse effects from the nonsteroidal antiinflammatory agent (ie, gastrointestinal, renal effects) Details Feverfew Diclofenac Transdermal Patch Flector Increased risk of adverse effects from the nonsteroidal antiinflammatory agent (ie, gastrointestinal, renal effects) Details Feverfew Etodolac Lodine Increased risk of adverse effects from the nonsteroidal antiinflammatory agent (ie, gastrointestinal, renal effects) Details Feverfew Fenoprofen Fenopron Increased risk of adverse effects from the nonsteroidal antiinflammatory agent (ie, gastrointestinal, renal effects) Details Feverfew Flurbiprofen Ansaid Increased risk of adverse effects from the nonsteroidal antiinflammatory agent (ie, gastrointestinal, renal effects) Details Feverfew Flurbiprofen Ophthalmic Ocufen Increased risk of adverse effects from the nonsteroidal antiinflammatory agent (ie, gastrointestinal, renal effects) Details Feverfew Ibuprofen Addaprin Increased risk of adverse effects from the nonsteroidal antiinflammatory agent (ie, gastrointestinal, renal effects) Details Feverfew Ketoprofen Actron® Increased risk of adverse effects from the nonsteroidal antiinflammatory agent (ie, gastrointestinal, renal effects) Details Feverfew Ketorolac Acular Increased risk of adverse effects from the nonsteroidal antiinflammatory agent (ie, gastrointestinal, renal effects) Details Feverfew Ketorolac Injection Acular Increased risk of adverse effects from the nonsteroidal antiinflammatory agent (ie, gastrointestinal, renal effects) Details Feverfew Ketorolac Nasal Spray Sprix Increased risk of adverse effects from the nonsteroidal antiinflammatory agent (ie, gastrointestinal, renal effects) Details Feverfew Ketorolac Ophthalmic Acular Increased risk of adverse effects from the nonsteroidal antiinflammatory agent (ie, gastrointestinal, renal effects) Details Feverfew Meclofenamate Meclodium® Increased risk of adverse effects from the nonsteroidal antiinflammatory agent (ie, gastrointestinal, renal effects) Details Feverfew Mefenamic Acid Ponstel® Increased risk of adverse effects from the nonsteroidal antiinflammatory agent (ie, gastrointestinal, renal effects) Details Feverfew Meloxicam Alloxate Increased risk of adverse effects from the nonsteroidal antiinflammatory agent (ie, gastrointestinal, renal effects) Details Feverfew Meloxicam Injection Alloxate Increased risk of adverse effects from the nonsteroidal antiinflammatory agent (ie, gastrointestinal, renal effects) Details Feverfew Nabumetone Relafen Increased risk of adverse effects from the nonsteroidal antiinflammatory agent (ie, gastrointestinal, renal effects) Details Feverfew Naproxen Aleve Increased risk of adverse effects from the nonsteroidal antiinflammatory agent (ie, gastrointestinal, renal effects) Details

Moderate

Feverfew Anagrelide Agrylin Increased risk of bleeding Details Feverfew Becaplermin Topical Regranex Increased risk of bleeding Details Feverfew Clopidogrel Plavix Increased risk of bleeding Details Feverfew Dalteparin Injection Fragmin Increased risk of bleeding Details Feverfew Defibrotide Injection Defitelio Increased risk of bleeding Details Feverfew Dipyridamole Permole® Increased risk of bleeding Details Feverfew Enoxaparin Lovenox Increased risk of bleeding Details Feverfew Enoxaparin Injection Lovenox Increased risk of bleeding Details Feverfew Epoprostenol Flolan Increased risk of bleeding Details Feverfew Fondaparinux Arixtra Increased risk of bleeding Details Feverfew Fondaparinux Injection Arixtra Increased risk of bleeding Details Feverfew Heparin Increased risk of bleeding Details Feverfew Heparin Injection Lipo-Hepin® Increased risk of bleeding Details Feverfew Iloprost Aurlumyn Increased risk of bleeding Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.