Itraconazole

Contraindicated

Itraconazole Colchicine Colcrys Explained Increased colchicine exposure and an increased risk of colchicine toxicity Details Itraconazole Simvastatin Flolipid Explained Increased simvastatin exposure and an increased risk of myopathy and rhabdomyolysis Details Itraconazole Alfuzosin UroXatral Increased alfuzosin exposure Details Itraconazole Avanafil Stendra Increased avanafil exposure and an increased risk of avanafil-related adverse effects Details Itraconazole Dihydroergotamine Injection DHE-45® Injection An increased risk of ergotism (vasospasm leading to cerebral ischemia and/or ischemia of the extremities) Details Itraconazole Dihydroergotamine Nasal Spray Migranal An increased risk of ergotism (vasospasm leading to cerebral ischemia and/or ischemia of the extremities) Details Itraconazole Disopyramide Norpace Increased disopyramide exposure and an increased risk of cardiotoxicity (eg, QT interval prolongation, torsades de pointes, cardia... Details Itraconazole Dofetilide Tikosyn An increased risk of cardiotoxicity (QT interval prolongation, torsades de pointes, ventricular tachycardia, cardiac arrest, and/o... Details Itraconazole Felodipine Plendil® Increased felodipine exposure and potential cardiotoxicity Details Itraconazole Finerenone Kerendia Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Itraconazole Irinotecan Camptosar Increased irinotecan exposure Details Itraconazole Irinotecan Injection Camptosar Increased irinotecan exposure Details Itraconazole Irinotecan Lipid Complex Injection Onivyde® Increased irinotecan exposure Details Itraconazole Ivabradine Corlanor Increased ivabradine exposure, an increased risk of ivabradine-related adverse effects and an increased risk of QT prolongation Details Itraconazole Ketoconazole Topical Extina® Foam Increased itraconazole exposure, an increased ketoconazole exposure and an increased risk of QT interval prolongation Details Itraconazole Lovastatin Altocor® Increased lovastatin exposure and an increased risk of lovastatin-related adverse effects, such as an increased risk of myopathy a... Details Itraconazole Lurasidone Latuda Increased lurasidone exposure Details Itraconazole Methylergonovine Methergine An increased risk of ergotism (vasospasm leading to cerebral ischemia and/or ischemia of the extremities) Details Itraconazole Midazolam Nasal Spray Nayzilam Increased midazolam exposure and an increased risk of midazolam-related adverse effects (respiratory depression) Details Itraconazole Midazolam Injection Nayzilam Increased midazolam exposure and an increased risk of midazolam-related adverse effects (respiratory depression) Details Itraconazole Naloxegol Movantik Increased naloxegol exposure Details Itraconazole Nisoldipine Sular Increased nisoldipine exposure and an increased risk of nisoldipine-related adverse effects (including congestive heart failure) Details

Major

Itraconazole Acetaminophen And Codeine Capital® & Codeine Explained Increased codeine and morphine exposure Details Itraconazole Abametapir Explained Increased exposure of CYP3A4 substrate Details Itraconazole Clindamycin ANTIROBE Explained Increased CYP3A4 substrate exposure and an increased risk of CYP3A4 substrate-related adverse effects Details Itraconazole Omeprazole Gastrobim Explained Reduced itraconazole exposure, increased omeprazole exposure and an increased risk of omeprazole-related adverse effects Details Itraconazole Amitriptyline Elavil Explained An increased risk of QT interval prolongation and torsade de pointes Details Itraconazole Sertraline Explained An increased risk of QT interval prolongation Details Itraconazole Buprenorphine Belbuca Explained An increased risk of QT interval prolongation, increased buprenorphine exposure and an increased risk of buprenorphine-related adv... Details Itraconazole Relugolix Orgovyx Explained Increased relugolix exposure and an increased risk of QT interval prolongation Details Itraconazole Acalabrutinib Calquence Increased acalabrutinib exposure Details Itraconazole Ado-Trastuzumab Emtansine Injection KADCYLA Increased cytotoxic component DM1 (maytansine derivative) exposure and an increased risk of toxicity Details Itraconazole Aliskiren Tekturna Increased aliskiren exposure Details Itraconazole Alitretinoin Panretin Increased alitretinoin exposure and an increased risk of alitretinoin-related adverse effects Details Itraconazole Alpelisib Piqray Increased alpelisib exposure and an increased risk of alpelisib-related adverse effects and toxicity Details Itraconazole Amisulpride Injection Barhemsys Increased risk of serious ventricular arrhythmias such as torsades de pointes Details Itraconazole Apixaban Eliquis Explained Increased apixaban exposure and an increased risk of bleeding Details Itraconazole Arsenic Trioxide Trisenox Increased risk of QT-interval prolongation and torsade de pointes Details Itraconazole Aripiprazole Injection Abilify Increased ARIPiprazole exposure and an increased risk of QT interval prolongation Details Itraconazole Arsenic Trioxide Injection Trisenox Increased risk of QT-interval prolongation and torsade de pointes Details