Chlorzoxazone

Major

Chlorzoxazone Acetaminophen And Codeine Capital® & Codeine Explained Increased risk of profound sedation, respiratory depression, coma and death Details Chlorzoxazone Buprenorphine Belbuca Explained Enhanced neuromuscular blocking action and an increased risk of respiratory depression and CNS depression Details Chlorzoxazone Colchicine Colcrys Explained Increased colchicine exposure and an increased risk of colchicine-related toxicity Details Chlorzoxazone Azathioprine Azasan An increased risk of hepatotoxicity Details Chlorzoxazone Bedaquiline Sirturo Increased bedaquiline exposure Details Chlorzoxazone Butorphanol Injection Butorphic Increased risk of respiratory and CNS depression Details Chlorzoxazone Butorphanol Nasal Spray Stadol® NS Increased risk of respiratory and CNS depression Details Chlorzoxazone Cetirizine Injection Aller-Tec Increased risk of CNS depression Details Chlorzoxazone Cetirizine Ophthalmic Zerviate Increased risk of CNS depression Details Chlorzoxazone Diazepam Nasal Spray Valtoco Additive respiratory depression Details Chlorzoxazone Diazepam Rectal Diastat Additive respiratory depression Details Chlorzoxazone Doxorubicin Adriamycin Increased doxorubicin exposure and an increased risk of doxorubicin-related adverse reactions Details Chlorzoxazone Esketamine Nasal Spray Spravato Increased risk of sedation Details Chlorzoxazone Fentanyl Transdermal Patch Duragesic® Increased risk of profound sedation, respiratory depression, hypotension, coma and death Details Chlorzoxazone Finerenone Kerendia Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Chlorzoxazone Hydromorphone Injection Dilaudid Increased risk of profound sedation, respiratory depression, coma and death Details Chlorzoxazone Hydromorphone Rectal available generically Increased risk of profound sedation, respiratory depression, coma and death Details Chlorzoxazone Lacosamide Injection Motpoly An increased risk of CNS depression Details Chlorzoxazone Levodopa Oral Inhalation Inbrija An increased risk of CNS depression Details Chlorzoxazone Loperamide Diamode Increased loperamide exposure and an increased risk of loperamide-related adverse reactions Details Chlorzoxazone Mercaptopurine Purinethol® An increased risk of hepatotoxicity Details Chlorzoxazone Methotrexate Jylamvo Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Chlorzoxazone Methotrexate Injection Abitrexate® Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Chlorzoxazone Methylergonovine Methergine Increased methylergonovine exposure Details Chlorzoxazone Metoclopramide Injection Gimoti Increased risk of CNS depression Details Chlorzoxazone Metoclopramide Nasal Spray Gimoti Increased risk of CNS depression Details Chlorzoxazone Midazolam Nasal Spray Nayzilam Additive respiratory depression Details Chlorzoxazone Midazolam Injection Nayzilam Additive respiratory depression Details Chlorzoxazone Morphine Injection Astramorph® PF Increased risk of profound sedation, hypotension, coma and respiratory depression Details Chlorzoxazone Nalbuphine Injection Nubain® Increased risk of respiratory and CNS depression Details Chlorzoxazone Nifedipine Adalat® Increased NIFEdipine exposure Details

Moderate

Chlorzoxazone Clonidine Transdermal Patch Catapres An increased risk of sedation and somnolence Details Chlorzoxazone Dofetilide Tikosyn Increased dofetilide exposure Details Chlorzoxazone Hydrocortisone Ala-Cort Increased hydrocortisone exposure and an increased risk of hydrocortisone-related adverse reactions Details Chlorzoxazone Hydrocortisone Injection A-Hydrocort® Increased hydrocortisone exposure and an increased risk of hydrocortisone-related adverse reactions Details