Ciclesonide Nasal Spray

36 interactions 152 cited references
Also sold as: Omnaris Omnaris® Zetonna Zetonna®
About Ciclesonide Nasal Spray

Ciclesonide nasal spray is used to treat the symptoms of seasonal (occurs only at certain times of the year), and perennial (occurs all year round) allergic rhinitis. These symptoms include sneezing and stuffy, runny or itchy nose. Ciclesonide is in a class of medications called corticosteroids. It works by preventing… Read the full Ciclesonide Nasal Spray drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Major

Ciclesonide Nasal Spray Aspirin Acuprin® An increased risk of salicylism subsequent to withdrawal of corticosteroids Details Ciclesonide Nasal Spray Atazanavir Reyataz Increased corticosteroid exposure and an increased risk of corticosteroid-related adverse effects Details Ciclesonide Nasal Spray Bemiparin Increased risk of bleeding Details Ciclesonide Nasal Spray Carbamazepine Carbatrol Reduced corticosteroids exposure and reduced efficacy of corticosteroids Details Ciclesonide Nasal Spray Cobicistat Tybost Increased ciclesonide exposure and an increased risk for systemic corticosteroid effects Details Ciclesonide Nasal Spray Cosyntropin False elevations of plasma cortisol levels Details Ciclesonide Nasal Spray Darunavir Increased corticosteroid exposure Details Ciclesonide Nasal Spray Ethinyl Estradiol Increased corticosteroid exposure Details Ciclesonide Nasal Spray Fosphenytoin Cerebyx Reduced corticosteroid exposure Details Ciclesonide Nasal Spray Insulin Aspart, Recombinant Fiasp Reduced blood glucose lowering effect of insulin Details Ciclesonide Nasal Spray Insulin Glargine, Recombinant Basaglar Reduced blood glucose lowering effect of insulin Details Ciclesonide Nasal Spray Insulin Icodec-Abae Awiqli Reduced efficacy of insulin icodec-abae Details Ciclesonide Nasal Spray Itraconazole Sporanox Increased ciclesonide exposure and an increased risk of ciclesonide-related adverse effects Details Ciclesonide Nasal Spray Ketoconazole Extina Increased des-ciclesonide (active metabolite of ciclesonide) exposure Details Ciclesonide Nasal Spray Lutetium Lu 177 Dotatate Decreased lutetium Lu 177 dotatate efficacy Details Ciclesonide Nasal Spray Macimorelin False-positive or false-negative adult growth hormone deficiency diagnosis Details Ciclesonide Nasal Spray Nadroparin Increased risk of bleeding Details Ciclesonide Nasal Spray Nirmatrelvir Increased corticosteroid exposure and increased risk of Cushing syndrome and adrenal suppression Details Ciclesonide Nasal Spray Phenytoin Dilantin Reduced corticosteroid exposure Details Ciclesonide Nasal Spray Rabies Vaccine Imovax An inadequate immunological response to the vaccine, an increased risk of altered immunocompetence and reduced immune response to... Details Ciclesonide Nasal Spray Relacorilant Lifyorli Reduced relacorilant exposure and reduced efficacy of relacorilant, reduced glucocorticoids exposure and reduced efficacy of gluco... Details Ciclesonide Nasal Spray Ritonavir Norvir Increased glucocorticoid exposure and decreased plasma cortisol, and increased risk of Cushing syndrome and adrenal insufficiency Details Ciclesonide Nasal Spray Sargramostim Leukine Increased myeloproliferative effects of sargramostim Details Ciclesonide Nasal Spray Somatrogon-Ghla Reduced serum cortisol exposure, an increased risk of central (secondary) hypoadrenalism and attenuated growth-promoting effects o... Details Ciclesonide Nasal Spray Upadacitinib Rinvoq Increased risk of gastrointestinal perforations Details

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