Ciclesonide Nasal Spray

Name: Ciclesonide Nasal Spray Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

36 interactions 152 cited references

Also sold as: Omnaris Omnaris® Zetonna Zetonna®

About Ciclesonide Nasal Spray

Ciclesonide nasal spray is used to treat the symptoms of seasonal (occurs only at certain times of the year), and perennial (occurs all year round) allergic rhinitis. These symptoms include sneezing and stuffy, runny or itchy nose. Ciclesonide is in a class of medications called corticosteroids. It works by preventing… Read the full Ciclesonide Nasal Spray drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Mifepristone Desmopressin Upadacitinib Rabies Vaccine Phenytoin Nirmatrelvir

2 Contraindicated 25 Major 9 Moderate

All (36) Contraindicated (2) Major (25) Moderate (9)

Contraindicated

Ciclesonide Nasal Spray Desmopressin DDAVP Increased risk of severe hyponatremia Details Ciclesonide Nasal Spray Mifepristone Korlym An increased risk of autoimmune disorders and an increased risk of acute adrenal insufficiency, that may lead to exacerbation or d... Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.