Obeticholic Acid
25 interactions 61 cited referencesObeticholic acid is used alone or in combination with ursodiol (Actigall, Urso) to treat primary biliary cholangitis (PBC; a type of liver disease that destroys bile ducts, which allows bile to stay in the liver and cause damage) in people who cannot take ursodiol or in people who were not treated successfully with urs… Read the full Obeticholic Acid drug information page →
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Major
Obeticholic Acid Bendamustine Injection Belrapzo Increased bendamustine exposure and an increased risk of bendamustine-related adverse effects Details Obeticholic Acid Cyclosporine Injection Atopica Increased risk of liver dysfunction Details Obeticholic Acid Cyclosporine Ophthalmic Cequa Increased risk of liver dysfunction Details Obeticholic Acid Meloxicam Alloxate Increased meloxicam exposure and reduced meloxicam metabolic clearance Details Obeticholic Acid Meloxicam Injection Alloxate Increased meloxicam exposure and reduced meloxicam metabolic clearance Details Obeticholic Acid Belzutifan Welireg Increased belzutifan exposure and an increased risk of belzutifan-related adverse reactions Details Obeticholic Acid Bendamustine Increased bendamustine exposure and an increased risk of bendamustine-related adverse effects Details Obeticholic Acid Clomipramine Anafranil Increased clomiPRAMINE exposure Details Obeticholic Acid Cyclosporine Atopica Increased risk of liver dysfunction Details Obeticholic Acid Mavacamten Camzyos Increased mavacamten exposure and an increased risk of mavacamten-related adverse effects Details Obeticholic Acid Pimozide Increased pimozide exposure and an increased risk of pimozide-related adverse reactions Details Obeticholic Acid Triclabendazole Egaten Increased risk of QT interval prolongation Details Obeticholic Acid Voriconazole Vfend Increased voriconazole exposure and an increased risk of voriconazole-related adverse reactions Details Obeticholic Acid Warfarin Coumadin Increased warfarin exposure and an altered (increased or decreased) INR DetailsModerate
Obeticholic Acid Cholestyramine Resin Locholest® Reduced exposure and efficacy of obeticholic acid Details Obeticholic Acid Clopidogrel Plavix Reduced clopidogrel active metabolite exposure and reduced platelet inhibition Details Obeticholic Acid Colesevelam Welchol Reduced exposure and efficacy of obeticholic acid Details Obeticholic Acid Colestipol Colestid Reduced exposure and efficacy of obeticholic acid Details Obeticholic Acid Mexiletine Mexitil® Increased exposure to CYP1A2 substrate Details Obeticholic Acid Cholestyramine Prevalite Reduced exposure and efficacy of obeticholic acid Details Obeticholic Acid Pomalidomide Pomalyst Increased exposure to CYP1A2 substrate Details Obeticholic Acid Propranolol Hemangeol Increased propranolol exposure Details Obeticholic Acid Theophylline Accurbron® Increased exposure to CYP1A2 substrate Details Obeticholic Acid Tizanidine Increased exposure to CYP1A2 substrate DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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