Dextroamphetamine
56 interactions 7 explained in plain English
Also sold as:
Dexedrine
ProCentra
Zenzedi
Medically reviewed by
Dr. Brian Staiger, PharmD, BCPS
· Updated Jul 4, 2026
· Editorial policy
· Data sources
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Most serious with:
Linezolid Injection
Clonidine Transdermal Patch
Dexlansoprazole
Amitriptyline
Estradiol
Dacomitinib
Contraindicated
Dextroamphetamine Linezolid Injection Zyvox An increased risk of hypertensive crisis and an increased risk of serotonin syndrome DetailsMajor
Dextroamphetamine Acetaminophen And Codeine Capital® & Codeine Explained Increased risk of serotonin syndrome Details Dextroamphetamine Omeprazole Gastrobim Explained Increased exposure to amphetamine Details Dextroamphetamine Amitriptyline Elavil Explained An increased risk of serotonin syndrome Details Dextroamphetamine Sertraline Explained Increased amphetamine exposure and an increased risk of serotonin syndrome Details Dextroamphetamine Albuterol Oral Inhalation Accuneb® Explained Increased d-amphetamine in the brain and an increased risk of potentiated cardiovascular events Details Dextroamphetamine Buprenorphine Belbuca Explained An increased risk of serotonin syndrome Details Dextroamphetamine Dupilumab Injection Dupixent Explained Increased dextroamphetamine or lisdexamfetamine (prodrug of dextroamphetamine) exposure and an increased risk of serotonin syndrom... Details Dextroamphetamine Acetazolamide Diamox® Sequels® Increased exposure to amphetamine Details Dextroamphetamine Asenapine Transdermal Patch Secuado Increased dextroamphetamine or lisdexamfetamine (prodrug of dextroamphetamine) exposure and an increased risk of serotonin syndrom... Details Dextroamphetamine Abiraterone Abirtega Increased amphetamine exposure and increased risk of serotonin syndrome Details Dextroamphetamine Alogliptin Nesina Increased dextroamphetamine or lisdexamfetamine (prodrug of dextroamphetamine) exposure and an increased risk of serotonin syndrom... Details Dextroamphetamine Butorphanol Injection Butorphic An increased risk of serotonin syndrome Details Dextroamphetamine Butorphanol Nasal Spray Stadol® NS An increased risk of serotonin syndrome Details Dextroamphetamine Clonidine Transdermal Patch Catapres Increased d-amphetamine in the brain and an increased risk of potentiated cardiovascular events Details Dextroamphetamine Dacomitinib Vizimpro Increased amphetamine exposure and increased risk of serotonin syndrome Details Dextroamphetamine Dexlansoprazole Dexilant Increased exposure to amphetamine Details Dextroamphetamine Diphenhydramine Injection Banophen Increased dextroamphetamine or lisdexamfetamine (prodrug of dextroamphetamine) exposure and an increased risk of serotonin syndrom... Details Dextroamphetamine Diphenhydramine Topical Afterbite with Antihistamine Increased dextroamphetamine or lisdexamfetamine (prodrug of dextroamphetamine) exposure and an increased risk of serotonin syndrom... Details Dextroamphetamine Dolasetron Anzemet An increased risk of serotonin syndrome Details Dextroamphetamine Dolasetron Injection Anzemet An increased risk of serotonin syndrome Details Dextroamphetamine Dronabinol Marinol Increased dextroamphetamine or lisdexamfetamine (prodrug of dextroamphetamine) exposure and an increased risk of serotonin syndrom... Details Dextroamphetamine Droxidopa Northera Increased d-amphetamine in the brain and an increased risk of potentiated cardiovascular events Details Dextroamphetamine Enasidenib Idhifa Increased dextroamphetamine or lisdexamfetamine (prodrug of dextroamphetamine) exposure and an increased risk of serotonin syndrom... Details Dextroamphetamine Esomeprazole Nexium Increased exposure to amphetamine Details Dextroamphetamine Esomeprazole Injection Nexium Increased exposure to amphetamine Details Dextroamphetamine Estradiol Delestrogen Increased dextroamphetamine or lisdexamfetamine (prodrug of dextroamphetamine) exposure and an increased risk of serotonin syndrom... Details Dextroamphetamine Estradiol Topical Divigel Increased dextroamphetamine or lisdexamfetamine (prodrug of dextroamphetamine) exposure and an increased risk of serotonin syndrom... Details Dextroamphetamine Estradiol Transdermal Patch Alora® Increased dextroamphetamine or lisdexamfetamine (prodrug of dextroamphetamine) exposure and an increased risk of serotonin syndrom... Details Dextroamphetamine Febuxostat Uloric Increased dextroamphetamine or lisdexamfetamine (prodrug of dextroamphetamine) exposure and an increased risk of serotonin syndrom... Details Dextroamphetamine Felodipine Plendil® Increased dextroamphetamine or lisdexamfetamine (prodrug of dextroamphetamine) exposure and an increased risk of serotonin syndrom... Details Dextroamphetamine Fentanyl Transdermal Patch Duragesic® An increased risk of serotonin syndrome Details Dextroamphetamine Flecainide Tambocor® Increased dextroamphetamine or lisdexamfetamine (prodrug of dextroamphetamine) exposure and an increased risk of serotonin syndrom... Details Dextroamphetamine Gefitinib Iressa Increased dextroamphetamine or lisdexamfetamine (prodrug of dextroamphetamine) exposure and an increased risk of serotonin syndrom... Details Dextroamphetamine Granisetron Transdermal Patch Sancuso An increased risk of serotonin syndrome Details Dextroamphetamine Granisetron Injection Granisol An increased risk of serotonin syndrome Details Dextroamphetamine Hydralazine Apresoline® Increased dextroamphetamine or lisdexamfetamine (prodrug of dextroamphetamine) exposure and an increased risk of serotonin syndrom... Details Dextroamphetamine Hydromorphone Injection Dilaudid Increased risk of serotonin syndrome Details Dextroamphetamine Hydromorphone Rectal available generically Increased risk of serotonin syndrome Details Dextroamphetamine Hydroxychloroquine Plaquenil An increased risk of seizures, increased dextroamphetamine or lisdexamfetamine (prodrug of dextroamphetamine) exposure and an incr... DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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