Insulin
130 interactions 3 explained in plain English
Also sold as:
Afrezza
Humulin R
Myxredlin
Novolin R
Medically reviewed by
Dr. Brian Staiger, PharmD, BCPS
· Updated Jul 4, 2026
· Editorial policy
· Data sources
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Most serious with:
Miglitol
Gemifloxacin
Metoclopramide Injection
Glipizide
Moxifloxacin Injection
Metoclopramide Nasal Spray
Major
Insulin Acarbose Prandase® Explained An increased risk of hypoglycemia Details Insulin Abiraterone Abirtega An increased risk of severe hypoglycemia Details Insulin Alogliptin Nesina An increased risk of hypoglycemia Details Insulin Betaxolol Betoptic S Increased or reduced blood glucose lowering effect of insulin and reduced symptoms of hypoglycemia Details Insulin Betaxolol Ophthalmic Betoptic® Increased or reduced blood glucose lowering effect of insulin and reduced symptoms of hypoglycemia Details Insulin Bisoprolol Zebeta® Increased or reduced blood glucose lowering effect of insulin and reduced symptoms of hypoglycemia Details Insulin Brexpiprazole Rexulti Reduced blood glucose lowering effect of insulin Details Insulin Canagliflozin Invokana An increased risk of hypoglycemia Details Insulin Chloroquine Aralen® Hypoglycemia Details Insulin Dapagliflozin Farxiga An increased risk of hypoglycemia Details Insulin Delafloxacin Baxdela Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Insulin Delafloxacin Injection Baxdela Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Insulin Droxidopa Northera Reduced blood glucose lowering effect of insulin Details Insulin Empagliflozin Glyxambi® (as a combination product containing Empagliflozin and Linagliptin) An increased risk of hypoglycemia Details Insulin Ertugliflozin Steglatro An increased risk of hypoglycemia Details Insulin Esmolol Brevibloc Increased or reduced blood glucose lowering effect of insulin and reduced symptoms of hypoglycemia Details Insulin Exenatide Injection Bydureon Increased risk of hypoglycemia Details Insulin Furosemide Injection Disal An increased risk of hyperglycemia and an increased insulin requirement Details Insulin Gatifloxacin Ophthalmic Zymar® Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Insulin Gemifloxacin Factive Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Insulin Glimepiride Amaryl An increased risk of hypoglycemia Details Insulin Glipizide Glucotrol An increased risk of hypoglycemia Details Insulin Hydroxychloroquine Plaquenil Enhanced hypoglycemic effect of antidiabetics and an increased risk of hypoglycemia Details Insulin Labetalol Normodyne® Increased or reduced blood glucose lowering effect of insulin and reduced symptoms of hypoglycemia Details Insulin Lanreotide Injection Somatuline An increased risk of hypoglycemia and impaired glucose regulation Details Insulin Levobunolol Ophthalmic AKBeta® Increased or reduced blood glucose lowering effect of insulin and reduced symptoms of hypoglycemia Details Insulin Levofloxacin Levaquin Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Insulin Levofloxacin Injection Levaquin Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Insulin Linagliptin Tradjenta An increased risk of hypoglycemia Details Insulin Liraglutide Injection Saxenda An increased risk of hypoglycemia Details Insulin Lumateperone Caplyta Reduced blood glucose lowering effect of insulin Details Insulin Lurasidone Latuda Reduced blood glucose lowering effect of insulin Details Insulin Metformin Fortamet® An increased risk of hypoglycemia Details Insulin Methylphenidate Adhansia XR® Reduced blood glucose lowering effect of insulin Details Insulin Methylphenidate Transdermal Patch Daytrana Reduced blood glucose lowering effect of insulin Details Insulin Metoclopramide Injection Gimoti Risk of hyperglycemia Details Insulin Metoclopramide Nasal Spray Gimoti Risk of hyperglycemia Details Insulin Miglitol Glyset® An increased risk of hypoglycemia Details Insulin Moxifloxacin Avelox Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Insulin Moxifloxacin Injection Avelox Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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