Topiramate

Major

Topiramate Acetaminophen And Codeine Capital® & Codeine Explained Increased risk of CNS depression and reduced codeine exposure Details Topiramate Amitriptyline Elavil Explained Increased amitriptyline exposure Details Topiramate Buprenorphine Belbuca Explained An increased risk of respiratory depression and CNS depression Details Topiramate Acetazolamide Diamox® Sequels® An increased risk of nephrolithiasis and severity of metabolic acidosis Details Topiramate Apixaban Eliquis Explained Decreased apixaban exposure and possible subtherapeutic anticoagulation which could lead to a thrombotic event Details Topiramate Aripiprazole Injection Abilify An increased risk of CNS depression Details Topiramate Asenapine Transdermal Patch Secuado An increased risk of CNS depression Details Topiramate Atogepant Qulipta Reduced atogepant exposure Details Topiramate Cariprazine Vraylar Explained Effects on the cariprazine exposure has not been evaluated and the net effect is unclear Details Topiramate Amlodipine Amvaz® Reduced amLODIPine exposure Details Topiramate Brinzolamide Ophthalmic Azopt An increased risk of nephrolithiasis and severity of metabolic acidosis Details Topiramate Butorphanol Injection Butorphic Increased risk of respiratory and CNS depression Details Topiramate Butorphanol Nasal Spray Stadol® NS Increased risk of respiratory and CNS depression Details Topiramate Calcifediol Rayaldee Altered serum levels of calcifediol Details Topiramate Cetirizine Injection Aller-Tec Increased risk of CNS depression Details Topiramate Cetirizine Ophthalmic Zerviate Increased risk of CNS depression Details Topiramate Diazepam Nasal Spray Valtoco An increased risk of CNS depression Details Topiramate Diazepam Rectal Diastat An increased risk of CNS depression Details Topiramate Diphenhydramine Injection Banophen An increased risk of CNS depression Details Topiramate Diphenhydramine Topical Afterbite with Antihistamine An increased risk of CNS depression Details Topiramate Dorzolamide Ophthalmic Trusopt® Ocumeter® Plus An increased risk of nephrolithiasis and severity of metabolic acidosis Details Topiramate Esketamine Nasal Spray Spravato Increased risk of sedation Details Topiramate Estradiol Delestrogen Reduced hormonal contraceptive exposure, reduced contraceptive efficacy and an increased risk of breakthrough bleeding/contracepti... Details Topiramate Estradiol Topical Divigel Reduced hormonal contraceptive exposure, reduced contraceptive efficacy and an increased risk of breakthrough bleeding/contracepti... Details Topiramate Estradiol Transdermal Patch Alora® Reduced hormonal contraceptive exposure, reduced contraceptive efficacy and an increased risk of breakthrough bleeding/contracepti... Details Topiramate Fentanyl Transdermal Patch Duragesic® Increased risk of CNS depression and reduced exposure of fentaNYL Details Topiramate Hydromorphone Injection Dilaudid Increased risk of respiratory and CNS depression Details Topiramate Hydromorphone Rectal available generically Increased risk of respiratory and CNS depression Details Topiramate Hydroxychloroquine Plaquenil Impaired antiepileptic activity Details Topiramate Lacosamide Injection Motpoly An increased risk of CNS depression Details Topiramate Levodopa Oral Inhalation Inbrija An increased risk of CNS depression Details Topiramate Levonorgestrel After banger Reduced levonorgestrel exposure and increased risk of breakthrough bleeding and/or contraceptive failure Details Topiramate Levonorgestrel Intrauterine System Kyleena Reduced levonorgestrel exposure and increased risk of breakthrough bleeding and/or contraceptive failure Details Topiramate Lithium Carbonate Lithobid Increased lithium exposure Details Topiramate Lumateperone Caplyta Reduced lumateperone exposure Details Topiramate Medroxyprogesterone Amen® Reduced hormonal contraceptive exposure, reduced contraceptive efficacy and an increased risk of breakthrough bleeding/contracepti... Details Topiramate Medroxyprogesterone Injection Depo-Provera Reduced hormonal contraceptive exposure, reduced contraceptive efficacy and an increased risk of breakthrough bleeding/contracepti... Details Topiramate Metformin Fortamet® An increased risk of lactic acidosis and reduced serum bicarbonate Details Topiramate Methazolamide Neptazane® An increased risk of nephrolithiasis and severity of metabolic acidosis Details Topiramate Metoclopramide Injection Gimoti Increased risk of CNS depression Details