Baricitinib

50 interactions 55 cited references

Also sold as: Olumiant Olumiant®

About Baricitinib

Baricitinib is used alone or with other medications to treat rheumatoid arthritis (condition in which the body attacks its own joints causing pain, swelling, and loss of function) in adults who have not responded well to one or more tumor necrosis factor (TNF) inhibitor medication(s). It is also used for the treatment… Read the full Baricitinib drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Ixekizumab Injection Cholera Vaccine, Live Bacillus Of Calmette And Guerin Vaccine, Live Certolizumab Pegol Adalimumab Adenovirus Vaccine Type 4, Live

46 Major 4 Moderate

All (50) Major (46) Moderate (4)

Major

Baricitinib Abatacept Injection Orencia An increased risk of infection Details Baricitinib Adalimumab Injection Abrilada An increased risk of infection Details Baricitinib Anakinra Kineret An increased risk of infection Details Baricitinib Abatacept Orencia An increased risk of infection Details Baricitinib Adalimumab An increased risk of infection Details Baricitinib Adenovirus Vaccine Type 4, Live Potential risk of secondary transmission of infection by the live vaccine and reduced effectiveness of immunization Details Baricitinib Adenovirus Vaccine Type 7, Live Potential risk of secondary transmission of infection by the live vaccine and reduced effectiveness of immunization Details Baricitinib Bacillus Of Calmette And Guerin Vaccine, Live Potential risk of secondary transmission of infection by the live vaccine and reduced effectiveness of immunization Details Baricitinib Certolizumab Pegol An increased risk of infection Details Baricitinib Cholera Vaccine, Live Potential risk of secondary transmission of infection by the live vaccine and reduced effectiveness of immunization Details Baricitinib Dengue Tetravalent Vaccine, Live Potential risk of secondary transmission of infection by the live vaccine and reduced effectiveness of immunization Details Baricitinib Etanercept An increased risk of infection Details Baricitinib Fedratinib Inrebic An increased risk of infection Details Baricitinib Fexinidazole Increased exposure of OAT1/OAT3 substrate Details Baricitinib Gemfibrozil Lopid Increased baricitinib exposure Details Baricitinib Golimumab An increased risk of infection Details Baricitinib Guselkumab An increased risk of infection Details Baricitinib Infliximab Avsola An increased risk of infection Details Baricitinib Influenza Virus Vaccine, Live Potential risk of secondary transmission of infection by the live vaccine and reduced effectiveness of immunization Details Baricitinib Ixekizumab An increased risk of infection Details Baricitinib Leflunomide Arava Increased exposure of OAT3 substrate Details Baricitinib Measles Virus Vaccine, Live Potential risk of secondary transmission of infection by the live vaccine and reduced effectiveness of immunization Details Baricitinib Mumps Virus Vaccine, Live Potential risk of secondary transmission of infection by the live vaccine and reduced effectiveness of immunization Details Baricitinib Nitisinone Increased baricitinib exposure Details Baricitinib Poliovirus Vaccine, Live Potential risk of secondary transmission of infection by the live vaccine and reduced effectiveness of immunization Details Baricitinib Probenecid Increased baricitinib exposure Details Baricitinib Rituximab An increased risk of infection Details Baricitinib Rotavirus Vaccine, Live Potential risk of secondary transmission of infection by the live vaccine and reduced effectiveness of immunization Details Baricitinib Rubella Virus Vaccine, Live Potential risk of secondary transmission of infection by the live vaccine and reduced effectiveness of immunization Details Baricitinib Ruxolitinib Jakafi An increased risk of infection Details Baricitinib Sarilumab An increased risk of infection Details Baricitinib Secukinumab An increased risk of infection Details Baricitinib Smallpox Monkeypox Vaccine Potential risk of secondary transmission of infection by the live vaccine and reduced effectiveness of immunization Details Baricitinib Teriflunomide Aubagio Increased exposure of OAT3 substrate Details Baricitinib Tocilizumab Actemra An increased risk of infection Details Baricitinib Typhoid Vaccine, Live Vivotif Potential risk of secondary transmission of infection by the live vaccine and reduced effectiveness of immunization Details Baricitinib Upadacitinib Rinvoq An increased risk of infection Details Baricitinib Ustekinumab An increased risk of infection Details Baricitinib Vadadustat Vafseo Increased OAT3 substrate exposure and an increased risk of OAT3 substrate-related adverse effect Details Baricitinib Varicella Virus Vaccine, Live Potential risk of secondary transmission of infection by the live vaccine and reduced effectiveness of immunization Details

Check another drug

Still have questions about this combination?

Every question gets a real answer from a licensed pharmacist — free, and usually within a day.

Ask the pharmacist

Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.