Ketotifen

Name: Ketotifen Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

8 interactions 133 cited references

Also sold as: Alaway Claritin Eye Wal-Zyr Itchy Eye Zaditor

Read the full Ketotifen drug information page

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Tranylcypromine Hydroxychloroquine Amifampridine Bupropion Clomipramine Donepezil

1 Contraindicated 7 Major

All (8) Contraindicated (1) Major (7)

Contraindicated

Ketotifen Tranylcypromine Parnate Increased risk of anticholinergic effects Details

Major

Ketotifen Hydroxychloroquine Plaquenil An increased risk of seizures Details Ketotifen Amifampridine Increased risk of seizures Details Ketotifen Bupropion Aplenzin Increased risk of seizures Details Ketotifen Clomipramine Anafranil Increased risk of seizures Details Ketotifen Donepezil Adlarity Reduced seizure threshold Details Ketotifen Pitolisant Wakix Reduced efficacy of pitolisant Details Ketotifen Tramadol ConZip An increased risk of seizure Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.