Methyldopa
53 interactions 516 cited referencesMethyldopa is an antihypertensive medication used to treat high blood pressure. Read the full Methyldopa drug information page →
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Contraindicated
Methyldopa Linezolid Injection Zyvox Hypertensive crisis (headache, palpitation, neck stiffness) Details Methyldopa Isocarboxazid Marplan Hypertensive crisis (headache, palpitation, neck stiffness) Details Methyldopa Linezolid Zyvox Hypertensive crisis (headache, palpitation, neck stiffness) Details Methyldopa Methylene Blue Provayblue Hypertensive crisis (headache, palpitation, neck stiffness) Details Methyldopa Ozanimod Hypertensive crisis (headache, palpitation, neck stiffness) Details Methyldopa Phenelzine Nardil Hypertensive crisis (headache, palpitation, neck stiffness) Details Methyldopa Procarbazine Hypertensive crisis (headache, palpitation, neck stiffness) Details Methyldopa Rasagiline Azilect Hypertensive crisis (headache, palpitation, neck stiffness) Details Methyldopa Safinamide Xadago Hypertensive crisis (headache, palpitation, neck stiffness) Details Methyldopa Selegiline Anipryl Hypertensive crisis (headache, palpitation, neck stiffness) DetailsMajor
Methyldopa Entacapone Comtan An increased risk of tachycardia, hypertension, and arrhythmias Details Methyldopa Iobenguane I 131 Azedra Inaccurate dosimetry calculations or reduced efficacy Details Methyldopa Pseudoephedrine Afrinol® Loss of blood pressure control and possibly hypertensive urgency DetailsModerate
Methyldopa Atenolol Tenormin Exaggerated hypertensive response, tachycardia, or arrhythmias during physiologic stress or exposure to exogenous catecholamines Details Methyldopa Acebutolol Sectral® Exaggerated hypertensive response, tachycardia, or arrhythmias during physiologic stress or exposure to exogenous catecholamines Details Methyldopa Betaxolol Betoptic S Exaggerated hypertensive response, tachycardia, or arrhythmias during physiologic stress or exposure to exogenous catecholamines Details Methyldopa Betaxolol Ophthalmic Betoptic® Exaggerated hypertensive response, tachycardia, or arrhythmias during physiologic stress or exposure to exogenous catecholamines Details Methyldopa Bisoprolol Zebeta® Exaggerated hypertensive response, tachycardia, or arrhythmias during physiologic stress or exposure to exogenous catecholamines Details Methyldopa Esmolol Brevibloc Exaggerated hypertensive response, tachycardia, or arrhythmias during physiologic stress or exposure to exogenous catecholamines Details Methyldopa Labetalol Normodyne® Exaggerated hypertensive response, tachycardia, or arrhythmias during physiologic stress or exposure to exogenous catecholamines Details Methyldopa Levobunolol Ophthalmic AKBeta® Exaggerated hypertensive response, tachycardia, or arrhythmias during physiologic stress or exposure to exogenous catecholamines Details Methyldopa Lithium Carbonate Lithobid An increased risk of toxic side effects Details Methyldopa Alprenolol Exaggerated hypertensive response, tachycardia, or arrhythmias during physiologic stress or exposure to exogenous catecholamines Details Methyldopa Bevantolol Exaggerated hypertensive response, tachycardia, or arrhythmias during physiologic stress or exposure to exogenous catecholamines Details Methyldopa Bucindolol Exaggerated hypertensive response, tachycardia, or arrhythmias during physiologic stress or exposure to exogenous catecholamines Details Methyldopa Carteolol Exaggerated hypertensive response, tachycardia, or arrhythmias during physiologic stress or exposure to exogenous catecholamines Details Methyldopa Carvedilol Coreg Exaggerated hypertensive response, tachycardia, or arrhythmias during physiologic stress or exposure to exogenous catecholamines Details Methyldopa Celiprolol Exaggerated hypertensive response, tachycardia, or arrhythmias during physiologic stress or exposure to exogenous catecholamines Details Methyldopa Dicumarol An increased risk of bleeding Details Methyldopa Dilevalol Exaggerated hypertensive response, tachycardia, or arrhythmias during physiologic stress or exposure to exogenous catecholamines Details Methyldopa Ferric Ammonium Citrate Decreased methyldopa effectiveness Details Methyldopa Haloperidol CNS toxicity (dementia) or reversible parkinsonism Details Methyldopa Iron Decreased methyldopa effectiveness Details Methyldopa Levobunolol Betagan Exaggerated hypertensive response, tachycardia, or arrhythmias during physiologic stress or exposure to exogenous catecholamines Details Methyldopa Lithium An increased risk of toxic side effects Details Methyldopa Ma Huang Reduced hypotensive effect of methyldopa Details Methyldopa Metipranolol Exaggerated hypertensive response, tachycardia, or arrhythmias during physiologic stress or exposure to exogenous catecholamines Details Methyldopa Metoprolol Kapspargo Exaggerated hypertensive response, tachycardia, or arrhythmias during physiologic stress or exposure to exogenous catecholamines Details Methyldopa Nadolol Corgard Exaggerated hypertensive response, tachycardia, or arrhythmias during physiologic stress or exposure to exogenous catecholamines Details Methyldopa Nebivolol Bystolic Exaggerated hypertensive response, tachycardia, or arrhythmias during physiologic stress or exposure to exogenous catecholamines DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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