Pralatrexate

23 interactions
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 11, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

23 Moderate
All (23) Moderate (23)

Moderate

Pralatrexate Aspirin Acuprin® Increased pralatrexate exposure Details Pralatrexate Aspirin Rectal Aspirin Increased pralatrexate exposure Details Pralatrexate Bromfenac Ophthalmic Bromday® Increased pralatrexate exposure Details Pralatrexate Diclofenac Ophthalmic Voltaren® Eye Drops Increased pralatrexate exposure Details Pralatrexate Diclofenac Topical (Actinic Keratosis) Pennsaid Increased pralatrexate exposure Details Pralatrexate Diclofenac Topical (Arthritis Pain) Pennsaid® Increased pralatrexate exposure Details Pralatrexate Diclofenac Transdermal Patch Flector Increased pralatrexate exposure Details Pralatrexate Etodolac Lodine Increased pralatrexate exposure Details Pralatrexate Fenoprofen Fenopron Increased pralatrexate exposure Details Pralatrexate Flurbiprofen Ansaid Increased pralatrexate exposure Details Pralatrexate Flurbiprofen Ophthalmic Ocufen Increased pralatrexate exposure Details Pralatrexate Ibuprofen Addaprin Increased pralatrexate exposure Details Pralatrexate Ketoprofen Actron® Increased pralatrexate exposure Details Pralatrexate Ketorolac Acular Increased pralatrexate exposure Details Pralatrexate Ketorolac Injection Acular Increased pralatrexate exposure Details Pralatrexate Ketorolac Nasal Spray Sprix Increased pralatrexate exposure Details Pralatrexate Ketorolac Ophthalmic Acular Increased pralatrexate exposure Details Pralatrexate Meclofenamate Meclodium® Increased pralatrexate exposure Details Pralatrexate Mefenamic Acid Ponstel® Increased pralatrexate exposure Details Pralatrexate Meloxicam Alloxate Increased pralatrexate exposure Details Pralatrexate Meloxicam Injection Alloxate Increased pralatrexate exposure Details Pralatrexate Nabumetone Relafen Increased pralatrexate exposure Details Pralatrexate Naproxen Aleve Increased pralatrexate exposure Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.