Golimumab Injection

32 interactions 87 cited references
Also sold as: Simponi Simponi® Simponi® Aria
About Golimumab Injection

Golimumab injection (Simponi) is used to relieve the symptoms of certain autoimmune disorders (conditions in which the immune system attacks healthy parts of the body and causes pain, swelling, and damage) including: rheumatoid arthritis (condition in which the body attacks its own joints causing pain, swelling, and lo… Read the full Golimumab Injection drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Abatacept Adalimumab Adenovirus Vaccine Type 4, Live Adenovirus Vaccine Type 7, Live Anakinra Anifrolumab-Fnia
29 Major 3 Moderate
All (32) Major (29) Moderate (3)

Major

Golimumab Injection Abatacept Orencia An increased risk of infection Details Golimumab Injection Adalimumab An increased risk of infection and other potential pharmacological interactions Details Golimumab Injection Adenovirus Vaccine Type 4, Live An increased risk of infection by live vaccines Details Golimumab Injection Adenovirus Vaccine Type 7, Live An increased risk of infection by live vaccines Details Golimumab Injection Anakinra Kineret An increased risk of serious infections and neutropenia Details Golimumab Injection Anifrolumab-Fnia Saphnelo Additive effects due to duplication of therapy Details Golimumab Injection Azathioprine Azasan An increased risk of hepatotoxicity Details Golimumab Injection Bacillus Of Calmette And Guerin Vaccine, Live An increased risk of infection by live vaccines Details Golimumab Injection Baricitinib Olumiant An increased risk of infection Details Golimumab Injection Cholera Vaccine, Live An increased risk of infection by live vaccines Details Golimumab Injection Dengue Tetravalent Vaccine, Live An increased risk of infection by live vaccines Details Golimumab Injection Ebola Zaire Vaccine, Live An increased risk of infection by live vaccines Details Golimumab Injection Infliximab Avsola Increased immunosuppression and an increased risk of infections Details Golimumab Injection Influenza Virus Vaccine, Live An increased risk of infection by live vaccines Details Golimumab Injection Levoketoconazole Recorlev Increased risk of serious hepatotoxicity and drug-induced liver injury Details Golimumab Injection Measles Virus Vaccine, Live An increased risk of infection by live vaccines Details Golimumab Injection Mercaptopurine Purinethol® An increased risk of hepatotoxicity Details Golimumab Injection Methotrexate Jylamvo Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Golimumab Injection Mumps Virus Vaccine, Live An increased risk of infection by live vaccines Details Golimumab Injection Poliovirus Vaccine, Live An increased risk of infection by live vaccines Details Golimumab Injection Rituximab An increased risk of serious infections Details Golimumab Injection Rotavirus Vaccine, Live An increased risk of infection by live vaccines Details Golimumab Injection Rubella Virus Vaccine, Live An increased risk of infection by live vaccines Details Golimumab Injection Smallpox Monkeypox Vaccine An increased risk of infection by live vaccines Details Golimumab Injection Typhoid Vaccine, Live Vivotif An increased risk of infection by live vaccines Details Golimumab Injection Varicella Virus Vaccine, Live An increased risk of infection by live vaccines Details Golimumab Injection Vedolizumab An increased risk of infections Details Golimumab Injection Yellow Fever Vaccine Stamaril An increased risk of infection by live vaccines Details Golimumab Injection Zoster Vaccine, Live An increased risk of infection by live vaccines Details

Moderate

Golimumab Injection Cyclosporine Atopica Increased cycloSPORINE exposure Details Golimumab Injection Theophylline Accurbron® Increased theophylline exposure Details Golimumab Injection Warfarin Coumadin Increased warfarin exposure Details

Check another drug

Still have questions about this combination?

Every question gets a real answer from a licensed pharmacist — free, and usually within a day.

Ask the pharmacist
Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.