Alitretinoin

Name: Alitretinoin Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

4 interactions 23 cited references

Also sold as: Panretin Panretin®

About Alitretinoin

Alitretinoin is used to treat skin lesions associated with Kaposi's sarcoma. It helps stop the growth of Kaposi's sarcoma cells. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. Read the full Alitretinoin drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 12, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Itraconazole

1 Major 3 Moderate

All (4) Major (1) Moderate (3)

Major

Alitretinoin Itraconazole Sporanox Increased alitretinoin exposure and an increased risk of alitretinoin-related adverse effects Details

Moderate

Alitretinoin Simvastatin Flolipid Decreased simvastatin plasma concentrations Details Alitretinoin Ketoconazole Extina Increased alitretinoin plasma concentrations Details Alitretinoin Ketoconazole Topical Extina® Foam Increased alitretinoin plasma concentrations Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.