Morphine Sulfate Liposome
72 interactions 6 explained in plain English
Medically reviewed by
Dr. Brian Staiger, PharmD, BCPS
· Updated Jul 4, 2026
· Editorial policy
· Data sources
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
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Major
Morphine Sulfate Liposome Acetaminophen And Codeine Capital® & Codeine Explained Increased risk of respiratory and CNS depression and an increased risk of serotonin syndrome Details Morphine Sulfate Liposome Amitriptyline Elavil Explained Increased risk of urinary retention, severe constipation, paralytic ileus and an increased risk of serotonin syndrome Details Morphine Sulfate Liposome Sertraline Explained Increased risk of serotonin syndrome Details Morphine Sulfate Liposome Buprenorphine Belbuca Explained Reduced analgesic effect or precipitation of withdrawal symptoms, and an increased risk of serotonin syndrome Details Morphine Sulfate Liposome Trospium / Xanomeline Cobenfy Explained Increased morphine exposure, increased trospium exposure and an increased risk of urinary retention, constipation and paralytic il... Details Morphine Sulfate Liposome Abrocitinib Cibinqo Explained Increased morphine exposure and an increased risk of morphine-related adverse effects (hypotension, respiratory depression, profou... Details Morphine Sulfate Liposome Alvimopan Entereg Decreased opioid efficacy and precipitation of opioid withdrawal Details Morphine Sulfate Liposome Aripiprazole Injection Abilify Increased risk of profound sedation, respiratory depression, hypotension, coma and death Details Morphine Sulfate Liposome Asenapine Transdermal Patch Secuado Increased risk of profound sedation, respiratory depression, hypotension, coma and death Details Morphine Sulfate Liposome Azithromycin AzaSite Increased morphine exposure and an increased risk of morphine-related adverse effects (hypotension, respiratory depression, profou... Details Morphine Sulfate Liposome Atorvastatin Atorvaliq Increased morphine exposure and an increased risk of morphine-related adverse effects (hypotension, respiratory depression, profou... Details Morphine Sulfate Liposome Aclidinium Oral Inhalation Tudorza Increased risk of urinary retention, severe constipation, and paralytic ileus Details Morphine Sulfate Liposome Alogliptin Nesina Increased morphine exposure and an increased risk of morphine-related adverse effects (hypotension, respiratory depression, profou... Details Morphine Sulfate Liposome Atropine Ophthalmic Atropine Care 1% Increased risk of urinary retention, severe constipation, and paralytic ileus Details Morphine Sulfate Liposome Butorphanol Injection Butorphic Reduced analgesic effect or precipitation of withdrawal symptoms, and an increased risk of serotonin syndrome Details Morphine Sulfate Liposome Butorphanol Nasal Spray Stadol® NS Reduced analgesic effect or precipitation of withdrawal symptoms, and an increased risk of serotonin syndrome Details Morphine Sulfate Liposome Canagliflozin Invokana Increased morphine exposure and an increased risk of morphine-related adverse effects (hypotension, respiratory depression, profou... Details Morphine Sulfate Liposome Capmatinib Tabrecta Increased morphine exposure and an increased risk of morphine-related adverse effects (hypotension, respiratory depression, profou... Details Morphine Sulfate Liposome Captopril Capoten® Increased morphine exposure and an increased risk of morphine-related adverse effects (hypotension, respiratory depression, profou... Details Morphine Sulfate Liposome Cetirizine Injection Aller-Tec Increased risk of CNS depression Details Morphine Sulfate Liposome Cetirizine Ophthalmic Zerviate Increased risk of CNS depression Details Morphine Sulfate Liposome Clopidogrel Plavix Reduced efficacy of clopidogrel Details Morphine Sulfate Liposome Cyclopentolate Ophthalmic Akpentolate® Increased risk of urinary retention, severe constipation, and paralytic ileus Details Morphine Sulfate Liposome Cyclosporine Injection Atopica Increased morphine exposure and an increased risk of morphine-related adverse effects (hypotension, respiratory depression, profou... Details Morphine Sulfate Liposome Cyclosporine Ophthalmic Cequa Increased morphine exposure and an increased risk of morphine-related adverse effects (hypotension, respiratory depression, profou... Details Morphine Sulfate Liposome Diazepam Nasal Spray Valtoco Increased risk of profound sedation, respiratory depression, hypotension, coma and death Details Morphine Sulfate Liposome Diazepam Rectal Diastat Increased risk of profound sedation, respiratory depression, hypotension, coma and death Details Morphine Sulfate Liposome Diphenhydramine Injection Banophen Increased risk of urinary retention, severe constipation, and paralytic ileus and an increased risk of profound sedation, respirat... Details Morphine Sulfate Liposome Diphenhydramine Topical Afterbite with Antihistamine Increased risk of urinary retention, severe constipation, and paralytic ileus and an increased risk of profound sedation, respirat... Details Morphine Sulfate Liposome Dolasetron Anzemet Increased risk of serotonin syndrome Details Morphine Sulfate Liposome Dolasetron Injection Anzemet Increased risk of serotonin syndrome Details Morphine Sulfate Liposome Elacestrant Orserdu Increased morphine exposure and an increased risk of morphine-related adverse effects (hypotension, respiratory depression, profou... Details Morphine Sulfate Liposome Enasidenib Idhifa Increased morphine exposure and an increased risk of morphine-related adverse effects (hypotension, respiratory depression, profou... Details Morphine Sulfate Liposome Entrectinib Rozlytrek Increased morphine exposure and an increased risk of morphine-related adverse effects (hypotension, respiratory depression, profou... Details Morphine Sulfate Liposome Esketamine Nasal Spray Spravato Increased risk of sedation Details Morphine Sulfate Liposome Felodipine Plendil® Increased morphine exposure and an increased risk of morphine-related adverse effects (hypotension, respiratory depression, profou... Details Morphine Sulfate Liposome Fentanyl Transdermal Patch Duragesic® Increased risk of respiratory and CNS depression and an increased risk of serotonin syndrome Details Morphine Sulfate Liposome Fostamatinib Tavalisse Increased morphine exposure and an increased risk of morphine-related adverse effects (hypotension, respiratory depression, profou... Details Morphine Sulfate Liposome Furosemide Injection Disal Reduced efficacy of diuretics DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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