Furosemide Injection

241 interactions 649 cited references

Also sold as: Disal Furoscix Furoscix® Lasix Lasix® Salix - substance

About Furosemide Injection

Furosemide injection is used in adults and children who cannot take oral medications or in emergency situations to treat edema (fluid retention; excess fluid held in body tissues) caused by various medical problems, including heart failure, pulmonary edema (excess fluid in the lungs), kidney, and liver disease. Furosem… Read the full Furosemide Injection drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Methenamine Desmopressin Vonoprazan Dexibuprofen Dasabuvir Dapagliflozin

2 Contraindicated 195 Major 41 Moderate 3 Minor

All (241) Contraindicated (2) Major (195) Moderate (41) Minor (3)

Contraindicated

Furosemide Injection Desmopressin DDAVP Increased risk of severe hyponatremia Details Furosemide Injection Methenamine Hiprex An increased risk of insoluble precipitate with formaldehyde in the urine Details

Major

Furosemide Injection Acarbose Prandase® An increased risk of hyperglycemia and an increased insulin requirement Details Furosemide Injection Aceclofenac Reduced diuretic effectiveness and possible nephrotoxicity Details Furosemide Injection Acemetacin Reduced diuretic effectiveness and possible nephrotoxicity Details Furosemide Injection Albiglutide An increased risk of hyperglycemia and an increased insulin requirement Details Furosemide Injection Albuterol ProAir An increased risk of ECG changes or hypokalemia Details Furosemide Injection Alogliptin Nesina An increased risk of hyperglycemia and an increased insulin requirement Details Furosemide Injection Amikacin Increased amikacin exposure and an increased risk of ototoxicity and/or nephrotoxicity Details Furosemide Injection Amikacin Liposome Increased amikacin exposure and an increased risk of ototoxicity and/or nephrotoxicity Details Furosemide Injection Amtolmetin Guacil Reduced diuretic effectiveness and possible nephrotoxicity Details Furosemide Injection Arsenic Trioxide Trisenox Increased risk of QT-interval prolongation and torsade de pointes Details Furosemide Injection Articaine An increased risk of methemoglobinemia Details Furosemide Injection Aspirin Acuprin® An increased risk of salicylate toxicity and reduced diuretic effectiveness and possible nephrotoxicity Details Furosemide Injection Azilsartan Edarbi Severe hypotension and deterioration in renal function, including renal failure Details Furosemide Injection Azilsartan Medoxomil Edarbi Severe hypotension and deterioration in renal function, including renal failure Details Furosemide Injection Benazepril Lotensin An increased risk of severe hypotension and deterioration in renal function, including renal failure Details Furosemide Injection Benzhydrocodone Reduced efficacy of diuretics Details Furosemide Injection Bepridil Hypokalemia and subsequent cardiotoxicity (torsades de pointes) Details Furosemide Injection Bromfenac Bromsite Reduced diuretic effectiveness and possible nephrotoxicity Details Furosemide Injection Bromocriptine Cycloset An increased risk of hyperglycemia and an increased insulin requirement Details Furosemide Injection Bufexamac Reduced diuretic effectiveness and possible nephrotoxicity Details Furosemide Injection Buprenorphine Belbuca Reduced efficacy of diuretics Details Furosemide Injection Canagliflozin Invokana An increased risk of hyperglycemia and an increased insulin requirement Details Furosemide Injection Candesartan Atacand Severe hypotension and deterioration in renal function, including renal failure Details Furosemide Injection Captopril Capoten® An increased risk of severe hypotension and deterioration in renal function, including renal failure Details Furosemide Injection Cefaclor Ceclor® Increased risk of cephalosporin-induced nephrotoxicity Details Furosemide Injection Cefadroxil Duricef® Increased risk of cephalosporin-induced nephrotoxicity Details Furosemide Injection Cefazolin Increased risk of cephalosporin-induced nephrotoxicity Details Furosemide Injection Cefdinir Omnicef® Increased risk of cephalosporin-induced nephrotoxicity Details Furosemide Injection Cefepime An increased risk of nephrotoxicity Details Furosemide Injection Cefixime Suprax Increased risk of cephalosporin-induced nephrotoxicity Details Furosemide Injection Cefotetan Increased risk of cephalosporin-induced nephrotoxicity Details Furosemide Injection Cefoxitin Increased risk of cephalosporin-induced nephrotoxicity Details Furosemide Injection Cefpodoxime Banan® Increased risk of cephalosporin-induced nephrotoxicity Details Furosemide Injection Cefprozil Cefzil® Increased risk of cephalosporin-induced nephrotoxicity Details Furosemide Injection Ceftaroline Fosamil Increased risk of cephalosporin-induced nephrotoxicity Details Furosemide Injection Ceftazidime An increased risk of nephrotoxicity Details Furosemide Injection Ceftobiprole Medocaril Increased risk of cephalosporin-induced nephrotoxicity Details Furosemide Injection Ceftriaxone Increased risk of cephalosporin-induced nephrotoxicity Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.