Axitinib Interactions
Axitinib is used alone to treat advanced renal cell carcinoma (RCC, a type of cancer that begins in the cells of the kidneys) in people who have not been treated successfully with another medication. Axitinib is used in combination with avelumab (Bavencio) or pembrolizumab (Keytruda) to treat advanced renal cell carcinoma. Axitinib is in a class of medications called kinase inhibitors. It works by blocking the action of an abnormal protein that signals cancer cells to multiply. This helps slow or stop the spread of cancer cells.
Brand Names Associated with Axitinib
- Axitinib
- Inlyta®
Have a question about an interaction not listed below?
Ask our clinical pharmacists directly!
Reach out to usClick the drug name (listed by the generic name) to view specific drug-drug interaction details.
- Major
- Clarithromycin
- Carbamazepine
- Ketoconazole
- Crizotinib
- Enzalutamide
- Abametapir
- Asciminib
- Atazanavir
- Avacopan
- Boceprevir
- Bosentan
- Ceritinib
- Conivaptan
- Daridorexant
- Efavirenz
- Etravirine
- Fedratinib
- Fexinidazole
- Fosnetupitant
- Fosphenytoin
Return To Drug Interaction Homepage
What Do The Severity Ratings Mean?
Contraindicated
These drugs, generally, should not be used together simultaneously due to the high risk of severe adverse effects. Combining these medications can lead to dangerous health outcomes and should be strictly avoided unless otherwise instructed by your provider.
Major
This interaction could result in very serious and potentially life-threatening consequences. If you are taking this drug combination, it is very important to be under close medical supervision to minimize severe side effects and ensure your safety. It may be necessary to change a medication or dosage to prevent harm.
Moderate
This interaction has the potential to worsen your medical condition or alter the effectiveness of your treatment. It's important that you are monitored closely and you potentially may need to make adjustments in your treatment plan or drug dosage to maintain optimal health.
Minor
While this interaction is unlikely to cause significant problems, it could intensify side effects or reduce the effectiveness of one or both medications. Monitoring for changes in symptoms and your condition is recommended, and adjustments may be made if needed to manage any increased or more pronounced side effects.
Disclaimer: The information provided on this page is for informational purposes only and should not be considered medical advice. Always consult with a qualified healthcare professional regarding your specific circumstances and medical conditions.
Drug interaction information is compilated from several drug compendia, including:
- Gold Standard Drug Database
- Micromedix
- Lexicomp
- PubMed
The information posted is fact-checked by HelloPharmacist clinicians and reviewed quarterly.