Daratumumab Injection

15 interactions 290 cited references
Also sold as: Darzalex Darzalex®
About Daratumumab Injection

Daratumumab injection is used alone or in combination with other medications to treat multiple myeloma (a type of cancer of the bone marrow) in newly diagnosed people and in people who have not improved with treatment or who have improved after treatment with other medications but the condition returned. Daratumumab is… Read the full Daratumumab Injection drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Typhoid Vaccine Mumps Virus Vaccine, Live Rubella Virus Vaccine, Live Smallpox Monkeypox Vaccine Measles Virus Vaccine, Live Varicella Virus Vaccine, Live
9 Contraindicated 6 Major
All (15) Contraindicated (9) Major (6)

Contraindicated

Daratumumab Injection Bacillus Of Calmette And Guerin Vaccine, Live An increased risk of infection by the live vaccine Details Daratumumab Injection Dengue Tetravalent Vaccine, Live An increased risk of infection by the live vaccine Details Daratumumab Injection Measles Virus Vaccine, Live An increased risk of infection by the live vaccine Details Daratumumab Injection Mumps Virus Vaccine, Live An increased risk of infection by the live vaccine Details Daratumumab Injection Rubella Virus Vaccine, Live An increased risk of infection by the live vaccine Details Daratumumab Injection Smallpox Monkeypox Vaccine An increased risk of infection by the live vaccine Details Daratumumab Injection Typhoid Vaccine Typhim VI® An increased risk of infection by the live vaccine Details Daratumumab Injection Varicella Virus Vaccine, Live An increased risk of infection by the live vaccine Details Daratumumab Injection Yellow Fever Vaccine Stamaril An increased risk of infection by the live vaccine Details

Major

Daratumumab Injection Adenovirus Vaccine Type 4, Live An increased risk of infection by the live vaccine Details Daratumumab Injection Adenovirus Vaccine Type 7, Live An increased risk of infection by the live vaccine Details Daratumumab Injection Cholera Vaccine Ipol An increased risk of infection by the live vaccine Details Daratumumab Injection Ebola Zaire Vaccine, Live An increased risk of infection by the live vaccine Details Daratumumab Injection Influenza Virus Vaccine, Live An increased risk of infection by the live vaccine Details Daratumumab Injection Rotavirus Vaccine, Live An increased risk of infection by the live vaccine Details

Check another drug

Still have questions about this combination?

Every question gets a real answer from a licensed pharmacist — free, and usually within a day.

Ask the pharmacist
Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.