Meloxicam

347 interactions 288 cited references
Also sold as: Alloxate Anjeso Loxicom Meloxidyl Meloxivet Metacam Mobic Mobic® Ostilox Qamzova Qmiiz Vivlodex Xifyrm Zybic
About Meloxicam

Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain, swelling, and stiffness from arthritis. Read the full Meloxicam drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Ketorolac Injection Ketorolac Ophthalmic Ketorolac Nasal Spray Ketorolac Furosemide Gossypol
4 Contraindicated 279 Major 64 Moderate
All (347) Contraindicated (4) Major (279) Moderate (64)

Contraindicated

Meloxicam Ketorolac Acular Enhanced gastrointestinal adverse effects (peptic ulcers, gastrointestinal bleeding and/or perforation) Details Meloxicam Ketorolac Injection Acular Enhanced gastrointestinal adverse effects (peptic ulcers, gastrointestinal bleeding and/or perforation) Details Meloxicam Ketorolac Nasal Spray Sprix Enhanced gastrointestinal adverse effects (peptic ulcers, gastrointestinal bleeding and/or perforation) Details Meloxicam Ketorolac Ophthalmic Acular Enhanced gastrointestinal adverse effects (peptic ulcers, gastrointestinal bleeding and/or perforation) Details

Major

Meloxicam Amitriptyline Elavil An increased risk of bleeding Details Meloxicam Sertraline An increased risk of bleeding Details Meloxicam Simvastatin Flolipid Increased meloxicam exposure and reduced meloxicam metabolic clearance Details Meloxicam Apixaban Eliquis An increased risk of bleeding Details Meloxicam Aspirin Acuprin® An increased risk of bleeding, increased risk of gastrointestinal adverse events and reduced renal function Details Meloxicam Aspirin Rectal Aspirin An increased risk of bleeding, increased risk of gastrointestinal adverse events and reduced renal function Details Meloxicam Betrixaban Bevyxxa® An increased risk of bleeding Details Meloxicam Anagrelide Agrylin An increased risk of bleeding Details Meloxicam Bromfenac Ophthalmic Bromday® Increased risk of bleeding Details Meloxicam Budesonide Entocort Increased risk of gastrointestinal ulcer or bleeding Details Meloxicam Budesonide Nasal Spray Rhinocort Increased risk of gastrointestinal ulcer or bleeding Details Meloxicam Budesonide Oral Inhalation Pulmicort Increased risk of gastrointestinal ulcer or bleeding Details Meloxicam Capecitabine Xeloda Increased exposure of CYP2C9 substrates and an increased risk of CYP2C9 substrates-related adverse effects Details Meloxicam Clopidogrel Plavix An increased risk of bleeding Details Meloxicam Cyclosporine Injection Atopica An increased risk of cycloSPORINE nephrotoxicity Details Meloxicam Cyclosporine Ophthalmic Cequa An increased risk of cycloSPORINE nephrotoxicity Details Meloxicam Dabigatran Pradaxa® An increased risk of bleeding Details Meloxicam Dabigatran Etexilate An increased risk of bleeding Details Meloxicam Dalteparin Injection Fragmin An increased risk of bleeding Details Meloxicam Deflazacort Emflaza Increased risk of gastrointestinal ulcer or bleeding Details Meloxicam Dexamethasone Injection Decadron Increased risk of gastrointestinal ulcer or bleeding Details Meloxicam Dexamethasone Ophthalmic Dexacidin® (as a combination product containing Dexamethasone, Neomycin, Polymyxin B) Increased risk of gastrointestinal ulcer or bleeding Details Meloxicam Diclofenac Ophthalmic Voltaren® Eye Drops Increased risk of bleeding Details Meloxicam Diclofenac Topical (Actinic Keratosis) Pennsaid Increased risk of bleeding Details Meloxicam Diclofenac Topical (Arthritis Pain) Pennsaid® Increased risk of bleeding Details Meloxicam Diclofenac Transdermal Patch Flector Increased risk of bleeding Details Meloxicam Digoxin Cardoxin® Increased digoxin exposure and prolonged half-life of digoxin Details Meloxicam Dipyridamole Permole® An increased risk of bleeding Details Meloxicam Disulfiram Antabuse Increased meloxicam exposure and reduced meloxicam metabolic clearance Details Meloxicam Edoxaban Savaysa An increased risk of bleeding Details Meloxicam Emtricitabine Emtriva Increased emtricitabine exposure and an increased risk of emtricitabine-related adverse effects Details Meloxicam Enoxaparin Lovenox An increased risk of bleeding Details Meloxicam Enoxaparin Injection Lovenox An increased risk of bleeding Details Meloxicam Epoprostenol Flolan An increased risk of bleeding Details Meloxicam Ertugliflozin Steglatro Increased meloxicam exposure and reduced meloxicam metabolic clearance Details Meloxicam Etodolac Lodine Increased risk of bleeding Details

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