Drug & supplement interaction

Rooibos + Meloxicam

Meloxicam brand names: Mobic, Vivlodex, Qmiiz ODT, Anjeso.

Moderate Interaction
Medically reviewed by · Updated October 2026
The bottom line Moderate

Rooibos has a moderate interaction with Meloxicam. Theoretically, taking rooibos with CYP2C9 substrates may increase the effects of CYP2C9 substrates.

Read the full interaction report
SeverityModerate
LikelihoodPossible
EvidenceD
What do Severity, Likelihood & Evidence mean?
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Interaction report

Rooibos and Meloxicam

Here is the interaction we found between these two, with the evidence behind it.

Moderate

CYTOCHROME P450 2C9 (CYP2C9) SUBSTRATES

Why this applies to Meloxicam

Meloxicam falls under CYTOCHROME P450 2C9 (CYP2C9) SUBSTRATES — the group Rooibos interacts with.

Theoretically, taking rooibos with CYP2C9 substrates may increase the effects of CYP2C9 substrates.
In vitro research shows that the methanol extract of rooibos leaves and stems inhibits CYP2C9 enzyme activity.
Severity Moderate Likelihood Possible Evidence D

Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.

Dr. Brian Staiger, PharmD, BCPS
Dr. Brian Staiger explains PharmD, Clinical Pharmacist

Here's the gist for meloxicam: your liver relies on an enzyme called CYP2C9 to clear this drug out of your body. Lab studies (using a concentrated rooibos extract, not regular tea) suggest rooibos might slow that enzyme down a bit. If it does, meloxicam could hang around longer and its effects could build up.

In real life, that might mean more of the usual NSAID side effects, like stomach upset, heartburn, fluid retention, or in rare cases higher risk of stomach bleeding or kidney strain. I want to be honest though: this is theoretical and based only on test-tube work, so a cup or two of rooibos tea is very unlikely to cause trouble. If you take concentrated rooibos supplements, just run it by your pharmacist or doctor first.

Contact Dr. Brian directly if you have additional questions on this interaction
References
  1. Fantoukh OI, Dale OR, Parveen A, et al. Safety Assessment of Phytochemicals Derived from the Globalized South African Rooibos Tea (Aspalathus linearis) through Interaction with CYP, PXR, and P-gp. J Agric Food Chem. 2019;67(17):4967-4975.

What These Ratings Mean

Every interaction above is graded three ways — here’s the key to each label.

Severity how clinically significant the interaction is
Major

Clinically significant. Avoid the combination, or use only under close professional supervision.

Moderate

Usually worth avoiding or managing — may need monitoring, a dose change, or timing apart.

Minor

Generally not serious. Be aware of it and mention it to your pharmacist.

Likelihood how strong the evidence is that the interaction actually happens in people
  • LikelyWell-controlled human studies have demonstrated the likely existence of this interaction.
  • ProbableInteraction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.
  • UnlikelyInteraction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Evidence the quality of the studies behind the rating (graded A–D)
  • AHigh-quality meta-analysis (quantitative systematic review).
  • BCase-control study.
  • CConsensus.
  • DAnecdotal evidence.

These ratings are for information only. Never start, stop, or otherwise change your therapy before speaking with your provider.

Keep it in perspective

Rooibos Also Interacts With Other Medications

Rooibos has 880 moderate known drug interactions in our database — the Meloxicam one above is one of them. If you take anything else, check it against the full list below.

Moderate 880 No known interaction 1,950 (incl. Meloxicam)
Taking anything else?

Check Another of Your Medications Against Rooibos

Covers the 2,830 medications we’ve checked against Rooibos. Pick one to open its full report.

From our Q&A

Questions About Rooibos or Meloxicam

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Rooibos or Meloxicam, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Meloxicam

This page covers Rooibos only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Meloxicam page lists 113 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Asarabacca (major), Beer (major), Siberian Cocklebur (major) and Wine (major).

By severity: 5 major · 81 moderate · 27 minor.

From our pharmacist’s overview on the Meloxicam page

“Most people take meloxicam (Mobic) daily for arthritis pain, which gives supplement interactions time to add up, so I read this list with real vigilance. Five of the 113 ingredients on file carry a major rating, and two are simply beer and wine, because alcohol plus any NSAID raises the odds of stomach bleeding.”

Reviewed by 2 · Jul 18, 2026

Open the Meloxicam interaction page

One more smart check

Taking Rooibos as Part of a Dietary Supplement Product? Check It for Interactions

We hold 142 real supplement products containing Rooibos, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Rooibos. Your product may carry other ingredients that interact with Meloxicam too, on top of Rooibos — and those would not show on this page. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Rooibos and Meloxicam Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Rooibos
Top half

#481 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Meloxicam
Top 25%

#662 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Supplement

About Rooibos

What is Rooibos?

Rooibos
  • Caffeine-free beverage
  • Antioxidant support
  • Heart health
  • Blood sugar support
  • Digestive upset
  • General wellness

Rooibos is a caffeine-free herbal tea from South Africa that is rich in antioxidants and generally considered safe as a beverage. While lab and early studies suggest possible benefits for heart health, blood sugar, and inflammation, strong human evidence is lacking for most medical uses. Enjoy it as a tea, but talk to your pharmacist or doctor before using concentrated extracts for health reasons.

Read the full Rooibos monograph & all interactions
Medication

About Meloxicam

What Is Meloxicam Used For?

Brand names: Mobic, Vivlodex, Qmiiz ODT, Anjeso

Meloxicam is used to relieve the signs and symptoms of osteoarthritis and rheumatoid arthritis. Some oral forms are also used for juvenile rheumatoid arthritis.

Not every product is approved for every use. Meloxicam capsules are indicated only for osteoarthritis pain. The intravenous injections Qamzova and Xifyrm are used in adults for moderate-to-severe pain, alone or with non-NSAID pain relievers.

See full Meloxicam drug information
Keep checking

Other Drugs & Rooibos

Browse every other medication we’ve checked against Rooibos — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
880Moderate
0Minor
1,949No known interaction
880 Moderate 1,949 No interaction
Moderate

880 interactions

Showing 60 of 880 moderate interactions — see all 880 on the Rooibos page.

No interaction 1,949 drugs checked — show the list

We also checked Rooibos against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 1,949 medications checked with no known interaction — see the full Rooibos list.

See the full Rooibos interactions page
See every supplement checked against Meloxicam, ranked by severity
Sources

Sources & How We Checked

Interaction details are evidence-graded and sourced from the Natural Medicines database. The medication overview comes from MedlinePlus.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Rooibos monograph › Uses, safety, and every drug interaction in one place Meloxicam supplement interactions › Every supplement checked against Meloxicam, ranked by severity Meloxicam drug information › The full plain-English guide to this medication Supplement interaction checker › Check any supplement or product against your medications Browse medications A–Z › Every drug we've checked against herbs & supplements Ask a pharmacist › Free, personal answer from our licensed team
Pharmacist Counseling Corner

Taking Rooibos and Meloxicam Together: Common Questions

Can you take Rooibos with Meloxicam?
There is a moderate interaction, so it may be acceptable with monitoring or timing changes — but check with your pharmacist first. Read the full details on this page and confirm with your pharmacist before combining them.
How serious is the Rooibos and Meloxicam interaction?
We rate it Moderate. This combination may require monitoring, a dose adjustment, or separating the times you take each one. Consult your pharmacist before using them together.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Meloxicam and Rooibos?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.